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4-CHLORO-2,6-DIMETHYLPYRIMIDINE

4-CHLORO-2,6-DIMETHYLPYRIMIDINE structure

CAS No.: 4472-45-1

Chemical Name:: 4-CHLORO-2,6-DIMETHYLPYRIMIDINE

Synonyms: Albb-005431;ASISCHEM A63094;TIMTEC-BB SBB010291;6-Chloro-2,4-dimethylpyrimidine;2,4-Dimethyl-6-chloropyrimidine;4-CHLORO-2,6-DIMETHYLPYRIMIDINE;Pyrimidine, 4-chloro-2,6-dimethyl-;4-Chloro-2,6-dimethylpyrimidine95%;4-CHLORO-2,6-DIMETHYLPYRIMIDINE 95%;4-Chloro-2,6-dimethylpyrimidine,97%

CBNumber:: CB2489784

Molecular Formula:: C6H7ClN2

Molecular Weight:: 142.59

MDL Number:: MFCD00234197

MOL File:: 4472-45-1.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:45

Product description	Number	Pack Size	Price
4-CHLORO-2,6-DIMETHYLPYRIMIDINE 97%	57908	1G	$30
4-CHLORO-2,6-DIMETHYLPYRIMIDINE 97%	57908	5G	$90
4-CHLORO-2,6-DIMETHYLPYRIMIDINE 97%	57908	25G	$240
4-Chloro-2,6-dimethylpyrimidine	C584950	10mg	$45
4-Chloro-2,6-dimethylpyrimidine 99%	OR55150	5g	$66
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4-CHLORO-2,6-DIMETHYLPYRIMIDINE Properties

Melting point	39-40 °C
Boiling point	180 °C
Density	1.184±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	liquid
pka	1.19±0.30(Predicted)
color	Clear, colourless
CAS DataBase Reference	4472-45-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Xi,Xn

Risk Statements

HazardClass

IRRITANT

HS Code

2933599590

NFPA 704

	1
2		0

4-CHLORO-2,6-DIMETHYLPYRIMIDINE price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AstaTech	57908	4-CHLORO-2,6-DIMETHYLPYRIMIDINE 97%	4472-45-1	1G	$30	2026-04-30	Buy
AstaTech	57908	4-CHLORO-2,6-DIMETHYLPYRIMIDINE 97%	4472-45-1	5G	$90	2026-04-30	Buy
AstaTech	57908	4-CHLORO-2,6-DIMETHYLPYRIMIDINE 97%	4472-45-1	25G	$240	2026-04-30	Buy
TRC	C584950	4-Chloro-2,6-dimethylpyrimidine	4472-45-1	10mg	$45	2021-12-16	Buy
Apolloscientific	OR55150	4-Chloro-2,6-dimethylpyrimidine 99%	4472-45-1	5g	$66	2021-12-16	Buy

Product number	Packaging	Price	Buy
57908	1G	$30	Buy
57908	5G	$90	Buy
57908	25G	$240	Buy
C584950	10mg	$45	Buy
OR55150	5g	$66	Buy

4-CHLORO-2,6-DIMETHYLPYRIMIDINE Chemical Properties,Uses,Production

Synthesis

6622-92-0

4472-45-1

General procedure for the synthesis of 4-chloro-2,6-dimethylpyrimidines from 2,4-dimethyl-6-hydroxypyrimidines: phosphorous trichloride (POCl3, 0.460 g, 3.0 mmol) was added to a solution of 2,4-dimethyl-6-hydroxypyrimidines (1.0 mmol) in toluene (15 mL), and the mixture was stirred for 3 hours under reflux conditions. Upon completion of the reaction, excess phosphorous trichloride was removed by distillation under reduced pressure and the reaction was subsequently quenched by the addition of ice water (10 mL). The pH of the reaction mixture was adjusted to 9-10 with sodium carbonate solution and then extracted with methyl tert-butyl ether (MTBE). The organic phase was dried with anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent to afford the target product 4-chloro-2,6-dimethylpyrimidine (yield: 82%). Mass spectrometry (ESI) showed a molecular ion peak (m/z) [M + H]+ of 143.1.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 10, p. 1769 - 1775
[2] Tetrahedron Letters, 1999, vol. 40, # 42, p. 7477 - 7478
[3] Patent: US5438058, 1995, A
[4] Patent: US6093718, 2000, A

4-CHLORO-2,6-DIMETHYLPYRIMIDINE synthesis

Synthesis of 4-CHLORO-2,6-DIMETHYLPYRIMIDINE from 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE

4-CHLORO-2,6-DIMETHYLPYRIMIDINE Preparation Products And Raw materials

Raw materials

2,4-Dimethylimidazole 4-Chloro-2,5-dimethylpyrimidine trichlorophosphate Pyrimidine, 5-chloro-2,4-dimethyl- (9CI) Toluene

2-chloro 3,5-dimethyl pyarazine 3-CHLORO-2,5-DIMETHYLPYRAZINE 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE 4,6-Dichloro-2-methylpyrimidine

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Preparation Products

DIETHYL PYRIMIDINE-4,6-DICARBOXYLATE DIMETHYL PYRIMIDINE-4,6-DICARBOXYLATE PYRIMIDINE-4,6-DICARBOXYLIC ACID Pyrimidine, 2,4-dimethyl- (6CI,7CI,8CI,9CI) 4-CHLORO-2-METHYLPYRIMIDINE

4-CHLORO-2,6-DIMETHYLPYRIMIDINE Suppliers

Global( 179)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10404	58
HaBo Hong Kong Co., Limited.	+86-25-18512596065	info@habotech.com	CHINA	933	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88298848	info@edengenechem.com	China	2176	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30227	58

Supplier	Advantage
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
HaBo Hong Kong Co., Limited.	58
Changzhou Ditong Chemical Co.,Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Career Henan Chemica Co	58

View Lastest Price from 4-CHLORO-2,6-DIMETHYLPYRIMIDINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-18	4-CHLORO-2,6-DIMETHYLPYRIMIDINE 4472-45-1	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
	2019-07-06	4-CHLORO-2,6-DIMETHYLPYRIMIDINE 4472-45-1	US $1.00 / kg	1kg	95%-99%	as request	Career Henan Chemical Co

4-CHLORO-2,6-DIMETHYLPYRIMIDINE
4472-45-1
US $1.10 / g
99.00%
Dideu Industries Group Limited

4-CHLORO-2,6-DIMETHYLPYRIMIDINE
4472-45-1
US $1.00 / kg
95%-99%
Career Henan Chemical Co

4-CHLORO-2,6-DIMETHYLPYRIMIDINE Spectrum

4-CHLORO-2,6-DIMETHYLPYRIMIDINE(4472-45-1)¹HNMR 4-CHLORO-2,6-DIMETHYLPYRIMIDINE(4472-45-1)FT-IR

4472-45-1(4-CHLORO-2,6-DIMETHYLPYRIMIDINE)Related Search:

Pyrimidine 5-Chloro-2,6-dimethylpyrimidine 2-CHLORO-4,6-DIMETHYLPYRIMIDINE,98.0+%(GC),2-CHLORO-4,6-DIMETHYLPYRIMIDINE 5-Bromo-4-chloro-2,6-dimethylpyrimidine 2-Amino-5-chloro-4,6-dimethylpyrimidine,5-Chloro-4,6-dimethylpyrimidine-2-amine

4-AMINO-2-CHLORO-6,7-DIMETHYLPYRIMIDINE,4-AMINO-5-CHLORO-2,6-DIMETHYLPYRIMIDINE 4-Chloro-5-chloro-2,6-dimethylpyrimidine 5-Bromo-2-chloro-4,6-dimethylpyrimidine 6-CHLORO-1,3-DIMETHYLPYRIMIDINE-2,6-1H,3H-DIONE,6-Chloro-1,3-dimethylpyrimidine-2,4-dione,6-CHLORO-1,3-DIMETHYLPYRIMIDINE-2,4(1H,3H)-DIONE 4-chloro-2,5-dimethylpyrimidine

4-CHLORO-5,6-DIMETHYLPYRIMIDINE ETHYL 6-CHLORO-2,5-DIMETHYLPYRIMIDINE-4-CARBOXYLATE

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4-CHLORO-2,6-DIMETHYLPYRIMIDINE TIMTEC-BB SBB010291 Pyrimidine, 4-chloro-2,6-dimethyl- (7CI,8CI,9CI) 4-Chloro-2,6-dimethylpyrimidine95% ASISCHEM A63094 4-CHLORO-2,6-DIMETHYLPYRIMIDINE 95% Albb-005431 2,4-Dimethyl-6-chloropyrimidine 6-Chloro-2,4-dimethylpyrimidine D241 4-Chloro-2,6-dimethyl-pyrimidine Pyrimidine, 4-chloro-2,6-dimethyl- 4-Chloro-2,6-dimethylpyrimidine,97% 4-CHLORO-2,6-DIMETHYLPYRIMIDINE ISO 9001：2015 REACH 4472-45-1 Heterocycle-Pyrimidine series alkyl chloride API intermediates PYRIMIDINE