ChemicalBook >> CAS DataBase List >>4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE

4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE

CAS No.
16355-28-5
Chemical Name:
4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE
Synonyms
NSC15457;6β-Hydroxycortisone;6β-Hydroxycortisone;6-BETA-HYDROCORTISONE;6-BETA-HYDROXYCORTISONE;6B-hydroxycortisone approx. 99%;4-Pregnene-6β,17α,21-triol-3,11,20-trione;4-PREGNEN-6-β, 17,21-TRIOL-3,11,20-TRIONE;4-PREGNEN-6β, 17, 21-TRIOL-3, 11, 20-TRIONE;4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE
CBNumber:
CB2672472
Molecular Formula:
C21H28O6
Molecular Weight:
376.44
MDL Number:
MFCD00057669
MOL File:
16355-28-5.mol
MSDS File:
SDS
Last updated:2023-05-15 10:43:32

4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE Properties

FDA UNII Z40D3IQ900

SAFETY

Risk and Safety Statements

WGK Germany  3

4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC H918450 6β-Hydroxycortisone 16355-28-5 5mg $180 2021-12-16 Buy
TRC H918450 6β-Hydroxycortisone 16355-28-5 50mg $1390 2021-12-16 Buy
American Custom Chemicals Corporation SHG0004696 4-PREGNEN-6-BETA,17,21-TRIOL-3,11,20-TRIONE 98.00% 16355-28-5 0.5G $1292.5 2021-12-16 Buy
Product number Packaging Price Buy
H918450 5mg $180 Buy
H918450 50mg $1390 Buy
SHG0004696 0.5G $1292.5 Buy

4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE Chemical Properties,Uses,Production

Uses

6β-Hydroxycortisone-d7 is the isotope labelled analog of 6β-Hydroxycortisone (H918450); a compound that can be used as a probe to detect inhibition of CYP3A4 in vivo.

Definition

ChEBI: 6beta-hydroxycortisone is a C21-steroid that is cortisone bearing an additional hydroxy substituent at the 6beta-position. It is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. It has a role as a probe and a human metabolite. It is a C21-steroid, a 6beta-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 21-hydroxy steroid, a 20-oxo steroid, a 17alpha-hydroxy steroid, an 11-oxo steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It is functionally related to a cortisone.

4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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Hubei Jusheng Technology Co.,Ltd.
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LGC Science (Shanghai) Ltd. 17717235263 cindy.yang@lgcgroup.com China 11572 58
6-BETA,17-ALPHA,21-TRIHYDROXY-4-PREGNENE-3,11,20-TRIONE 6-BETA-HYDROXYCORTISONE NSC15457 4-Pregnene-6β,17α,21-triol-3,11,20-trione 6β-Hydroxycortisone 6β,17,21-Trihydroxypregna-4-ene-3,11,20-trione 6β,17α,21-Trihydroxypregn-4-ene-3,11,20-trione 6B-hydroxycortisone approx. 99% 4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE 4-PREGNEN-6BETA,17ALPHA,21-TRIOL-3,11,20-TRIONE 4-PREGNENE-6-BETA,17-ALPHA,21-TRIOL-3,11,20-TRIONE (6R,8S,9S,10R,13S,14S,17R)-6,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione (6R,8S,9S,10R,13S,14S,17R)-6,17-Dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,10,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11(2H,6H)-dione 6-BETA-HYDROCORTISONE 4-PREGNEN-6-β, 17,21-TRIOL-3,11,20-TRIONE Pregn-4-ene-3,11,20-trione, 6,17,21-trihydroxy-, (6β)- 6β-Hydroxycortisone 4-PREGNEN-6β, 17, 21-TRIOL-3, 11, 20-TRIONE 16355-28-5 C21H28O6