AC-YVAD-AFC
- CAS No.
- 219137-85-6
- Chemical Name:
- AC-YVAD-AFC
- Synonyms
- AC-YVAD-AFC;AC-TYR-VAL-ALA-ASP-AFC;M.W. 719.67 C33H36F3N5O10;CASPASE-1 SUBSTRATE XII, FLUOROGENIC;CASPASE 1 (ICE) SUBSTRATE 2F, FLUOROGENIC;AC-TYR-VAL-ALA-ASP-7-AMINO-4-TRIFLUOROMETHYL COUMARIN;N-ACETYL-TYR-VAL-ALA-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;N-Acetyl-Tyr-Val-Ala-Asp-(7-amino-4-trifluoromethylcoumarin);Caspase-1 Substrate VI, Fluorogenic - CAS 219137-85-6 - Calbiochem;L-α-Asparagine, N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-
- CBNumber:
- CB2753902
- Molecular Formula:
- C33H36F3N5O10
- Molecular Weight:
- 719.66
- MDL Number:
- MFCD01318881
- MOL File:
- 219137-85-6.mol
AC-YVAD-AFC price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A9965 | N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin ≥95% (HPLC), powder | 219137-85-6 | 1mg | $178 | 2024-03-01 | Buy |
| Sigma-Aldrich | 688225 | Caspase-1 Substrate VI, Fluorogenic Fluorogenic caspase-1 substrate. | 219137-85-6 | 5mg | $293.4 | 2024-03-01 | Buy |
| Cayman Chemical | 17591 | Ac-YVAD-AFC ≥98% | 219137-85-6 | 1mg | $38 | 2024-03-01 | Buy |
| Cayman Chemical | 17591 | Ac-YVAD-AFC ≥98% | 219137-85-6 | 5mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 17591 | Ac-YVAD-AFC ≥98% | 219137-85-6 | 10mg | $220 | 2024-03-01 | Buy |
AC-YVAD-AFC Chemical Properties,Uses,Production
Description
Ac-YVAD-AFC is a substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-
Uses
N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin is a substrate whose amino acids are shown as a preferred cleavage site for Caspase-1 and 4. Useful for caspase research.
Definition
ChEBI: Ac-Tyr-Val-Ala-Asp-7-amino-4-trifluoromethylcoumarin is a tetrapeptide obtained by formal condensation of the C-terminal carboxy group of Ac-Tyr-Val-Ala-Asp with the amino group of 7-amino-4-trifluoromethylcoumarin. It has a role as a protease inhibitor. It is a tetrapeptide, a member of acetamides, a member of coumarins and an organofluorine compound. It is functionally related to a 7-amino-4-(trifluoromethyl)coumarin.
Biological Activity
Fluorogenic peptide substrate for caspase-1 (ICE).
AC-YVAD-AFC Preparation Products And Raw materials
Raw materials
Preparation Products
AC-YVAD-AFC Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| Nanjing TGpeptide | +86-13347807150 +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| DONBOO AMINO ACID COMPANY | +8613063595538 | donboo@donboo.com | China | 9365 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| VDM Biochemicals | 0330-2528181 | sales@vdmbio.com | United States | 510 | 64 |