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RARECHEM AL BW 0442

RARECHEM AL BW 0442 Structure
RARECHEM AL BW 0442 structure
CAS No.
56622-54-9
Chemical Name:
RARECHEM AL BW 0442
Synonyms
RARECHEM AL BW 0442;UKRORGSYN-BB BBV-059064;6-Methyl-3-PyridineMethanaMine;3-AMinoMethyl-6-Methylpyridine;(6-Methyl-3-pyridyl)methanamine;5-(Aminomethyl)-2-methylpyridine;3-PYRIDINEMETHANAMINE, 6-METHYL-;(6-METHYLPYRIDIN-3-YL)METHANAMINE;1-(6-METHYLPYRIDIN-3-YL)METHANAMINE;1-(6-Methyl-3-pyridinyl)MethanaMine
CBNumber:
CB2781947
Molecular Formula:
C7H10N2
Molecular Weight:
122.17
MDL Number:
MFCD06212657
MOL File:
56622-54-9.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:51
Product description Number Pack Size Price
3-Aminomethyl-6-methylpyridine A617015 100mg $165
3-Aminomethyl-6-methylpyridine 160441 100mg $460
3-Aminomethyl-6-methylpyridine A617015 1g $745
3-Aminomethyl-6-methylpyridine A617015 10g $1320
3-Aminomethyl-6-methylpyridine 3H32-1-AD 5G $1390
More product size
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RARECHEM AL BW 0442 Properties

Melting point 58-61 °C(Solv: heptane (142-82-5))
Boiling point 90-100 °C(Press: 4 Torr)
Density 1.027±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka pK1: 8.70(+1) (30°C)
Appearance White to yellow <58°C Solid,>61°C Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS07,GHS05,GHS06
Signal word  Danger
Hazard statements  H335-H301-H318-H315
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310
Hazard Codes  T
Risk Statements  25-37/38-41
Safety Statements  26-39-45
RIDADR  UN2811

RARECHEM AL BW 0442 price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A617015 3-Aminomethyl-6-methylpyridine 56622-54-9 100mg $165 2021-12-16 Buy
Usbiological 160441 3-Aminomethyl-6-methylpyridine 56622-54-9 100mg $460 2021-12-16 Buy
TRC A617015 3-Aminomethyl-6-methylpyridine 56622-54-9 1g $745 2021-12-16 Buy
TRC A617015 3-Aminomethyl-6-methylpyridine 56622-54-9 10g $1320 2021-12-16 Buy
SynQuest Laboratories 3H32-1-AD 3-Aminomethyl-6-methylpyridine 56622-54-9 5G $1390 2021-12-16 Buy
Product number Packaging Price Buy
A617015 100mg $165 Buy
160441 100mg $460 Buy
A617015 1g $745 Buy
A617015 10g $1320 Buy
3H32-1-AD 5G $1390 Buy

RARECHEM AL BW 0442 Chemical Properties,Uses,Production

Uses

3-Aminomethyl-6-methylpyridine is used in the synthesis of non-nucleoside phthalimide derivatives as HIV-1 reverse transcriptase inhibitors. Also used in in the discovery of potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with cytocrhome P450 CYP2C9 inhibitory activity.

Synthesis

6-METHYLNICOTINAMIDE

6960-22-1

RARECHEM AL BW 0442

56622-54-9

Example 4: 106 Synthesis of Step 1: Under argon protection, 3.00 g (22.0 mmol) of 6-methylnicotinamide was dissolved in 10 ml of tetrahydrofuran (THF), followed by the slow addition of 34 ml (34 mmol; 1.5 eq.) of 1 M lithium aluminium hydride in THF solution. After 45 min of reaction, 1.22 g (1.5 eq.) of lithium aluminum hydride dissolved in 40 ml of THF was added to the system. The reaction mixture was heated to 60°C under stirring and maintained at this temperature for 24 hours. Upon completion of the reaction, the reaction was carefully quenched sequentially with isopropanol, methanol and water at 0°C under stirring. Subsequently, the solvent was evaporated under reduced pressure. To the residue, 100 ml of 2N NaOH solution and 100 ml of dichloromethane (DCM) were added and centrifuged to separate the resulting white precipitate. The aqueous layer was extracted four times with 60 ml of DCM. All organic layers were combined, dried with anhydrous magnesium sulfate, and concentrated under reduced pressure to remove the solvent to afford 1.57 g (12.9 mmol; 58% yield) of the target product, 3-aminomethyl-6-methylpyridine (amine 2), which was used directly in the subsequent reaction without further purification.

References

[1] Patent: WO2006/128670, 2006, A1. Location in patent: Page/Page column 113

RARECHEM AL BW 0442 synthesis

3222-48-8
56622-54-9
Synthesis of RARECHEM AL BW 0442 from 5-CYANO-2-METHYLPYRIDINE

RARECHEM AL BW 0442 Preparation Products And Raw materials

Raw materials

5-(Azidomethyl)-2-methylpyridine 2-Chloro-6-methyl-3-pyridinecarbonitrile (6-Methylpyridin-3-yl)methanol 3-Cyano-6-methyl-2(1H)-pyridinone 5-CYANO-2-METHYLPYRIDINE
6-METHYLNICOTINAMIDE 6-Methylnicotinic acid Methyl 6-methylnicotinate Lithium Aluminum Hydride Tetrahydrofuran

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Preparation Products

RARECHEM AL BW 0442 Suppliers

Global( 75)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29837 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 24727 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 43339 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
Suzhou ARTK Medchem Co., Ltd. 		+86-512-68323658 +86-18168183658 sales1@artkmedchem.com China 39002 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53899 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39927 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Supplier Advantage
career henan chemical co 		58
Alchem Pharmtech,Inc. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Aladdin Scientific 		58
Suzhou ARTK Medchem Co., Ltd. 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58
Chongqing Chemdad Co., Ltd 		58
Amadis Chemical Company Limited 		58

View Lastest Price from RARECHEM AL BW 0442 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
RARECHEM AL BW 0442 pictures 2019-07-06 RARECHEM AL BW 0442
56622-54-9
 US $1.00 / KG 1KG 99% Customized Career Henan Chemical Co

RARECHEM AL BW 0442 Spectrum

RARECHEM AL BW 0442(56622-54-9)1HNMR

56622-54-9(RARECHEM AL BW 0442)Related Search:

5,7-DIMETHYLPYRIDO[2,3-D]PYRIMIDIN-4(3H)-ONE 2-AMINO-4,6-DIMETHYL-3-PYRIDINECARBOXAMIDE 6-METHYLNICOTINAMIDE 2-CHLORO-4,6-DIMETHYLNICOTINAMIDE 4,6-DIMETHYL-2-(([4-(TRIFLUOROMETHOXY)ANILINO]CARBONYL)AMINO)NICOTINAMIDE
6-METHYLPYRIDINE-3-CARBOTHIOAMIDE 2-CHLORO-6-METHYLNICOTINAMIDE 4-CHLORO-6-METHYL-2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDINE-1,3-DIONE 2,5-DICHLORO-4,6-DIMETHYLNICOTINAMIDE 4,6-DIMETHYL-2-(([3-(TRIFLUOROMETHYL)ANILINO]CARBONYL)AMINO)NICOTINAMIDE
2-benzyl-4-chloro-6-methyl-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-1,3-dione 6-(TERT-BUTYL)-4-CHLORO-2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDINE-1,3-DIONE 2-CHLORO-6-(2-THIENYL)-4-(TRIFLUOROMETHYL)NICOTINAMIDE 2-[(ANILINOCARBONYL)AMINO]-4,6-DIMETHYLNICOTINAMIDE 2-([(4-CHLOROANILINO)CARBONYL]AMINO)-4,6-DIMETHYLNICOTINAMIDE
4,6-DIMETHYL-2-[(4-TOLUIDINOCARBONYL)AMINO]NICOTINAMIDE 2-([(2-CHLOROANILINO)CARBONYL]AMINO)-4,6-DIMETHYLNICOTINAMIDE 2-([(3-CHLOROANILINO)CARBONYL]AMINO)-4,6-DIMETHYLNICOTINAMIDE

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RARECHEM AL BW 0442 (6-METHYLPYRIDIN-3-YL)METHANAMINE 1-(6-METHYLPYRIDIN-3-YL)METHANAMINE 1-(6-METHYLPYRIDIN-3-YL)METHANAMINE DIHYDROCHLORIDE 3-PYRIDINEMETHANAMINE, 6-METHYL- 5-(Aminomethyl)-2-methylpyridine C-(6-METHYL-PYRIDIN-3-YL)METHYLAMINE UKRORGSYN-BB BBV-059064 3-AMinoMethyl-6-Methylpyridine 6-Methyl-3-PyridineMethanaMine (6-Methyl-3-pyridyl)methanamine 1-(6-Methyl-3-pyridinyl)MethanaMine 56622-54-9