Osanetant
- CAS No.
- 160492-56-8
- Chemical Name:
- Osanetant
- Synonyms
- SR142801;SR-142801;Osanetant;Osanetant >=98% (HPLC);N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide;(R)-N-{{3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-methylacetamine;N-[1-[3-[(3R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-methylacetamide;AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-;Osanetant AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-
- CBNumber:
- CB31179397
- Molecular Formula:
- C35H41Cl2N3O2
- Molecular Weight:
- 606.62
- MDL Number:
- MFCD00938554
- MOL File:
- 160492-56-8.mol
- MSDS File:
- SDS
Boiling point | 727.9±60.0 °C(Predicted) |
---|---|
Density | 1.25 |
storage temp. | -20°C |
solubility | DMSO: soluble15mg/mL, clear |
form | powder |
pka | 8.33±0.10(Predicted) |
color | white to beige |
optical activity | [α]/D +18 to +24°, c = 1 in methanol |
FDA UNII | K7G81N94DT |
Osanetant price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML0798 | Osanetant ≥98% (HPLC) | 160492-56-8 | 5mg | $261 | 2024-03-01 | Buy |
Sigma-Aldrich | SML0798 | Osanetant ≥98% (HPLC) | 160492-56-8 | 25mg | $916 | 2024-03-01 | Buy |
ChemScene | CS-0003438 | Osanetant >98.0% | 160492-56-8 | 1mg | $260 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0005576 | OSANETANT 95.00% | 160492-56-8 | 5MG | $420.1 | 2021-12-16 | Buy |
ChemScene | CS-0003438 | Osanetant >98.0% | 160492-56-8 | 5mg | $780 | 2021-12-16 | Buy |
Osanetant Chemical Properties,Uses,Production
Biochem/physiol Actions
Osanetant is a selective antagonist of neurokinin 3 receptor NK3. Neurokinins (tachykinins) are members of a family of at least three neuropeptides, substance P, neurokinin A, and neurokinin B (NKB), with each mediating their biological effects through binding to a preferred G-protein-coupled receptor termed NK1, NK2, or NK3, respectively. All three NK receptors are expressed in regions of the central nervous system that are related to emotion and cognition (i.e., amygdala and hippocampus) and have been linked to various degrees in psychiatric disorders. Neurokinin receptors, including NK3 receptors, are also expressed in the motor and sensory systems of the digestive tract. Osanetant was in clinical trials for both irritable bowel syndrome and schizophrenia.
Osanetant Preparation Products And Raw materials
Raw materials
Preparation Products
Osanetant Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40068 | 58 |
Nanjing JinruiJiuAn Biotechnology Co., Ltd. | 025-58196018 800028039 | sales@fartop.net | China | 2231 | 55 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |