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Osanetant

CAS No.
160492-56-8
Chemical Name:
Osanetant
Synonyms
SR142801;SR-142801;Osanetant;Osanetant >=98% (HPLC);N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide;(R)-N-{{3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-methylacetamine;N-[1-[3-[(3R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-methylacetamide;AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-;Osanetant AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-
CBNumber:
CB31179397
Molecular Formula:
C35H41Cl2N3O2
Molecular Weight:
606.62
MDL Number:
MFCD00938554
MOL File:
160492-56-8.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:19

Osanetant Properties

Boiling point 727.9±60.0 °C(Predicted)
Density 1.25
storage temp. -20°C
solubility DMSO: soluble15mg/mL, clear
form powder
pka 8.33±0.10(Predicted)
color white to beige
optical activity [α]/D +18 to +24°, c = 1 in methanol
FDA UNII K7G81N94DT

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P264-P270-P280-P301+P312-P305+P351+P338-P337+P313
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26
WGK Germany  3

Osanetant price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0798 Osanetant ≥98% (HPLC) 160492-56-8 5mg $261 2024-03-01 Buy
Sigma-Aldrich SML0798 Osanetant ≥98% (HPLC) 160492-56-8 25mg $916 2024-03-01 Buy
ChemScene CS-0003438 Osanetant >98.0% 160492-56-8 1mg $260 2021-12-16 Buy
American Custom Chemicals Corporation INB0005576 OSANETANT 95.00% 160492-56-8 5MG $420.1 2021-12-16 Buy
ChemScene CS-0003438 Osanetant >98.0% 160492-56-8 5mg $780 2021-12-16 Buy
Product number Packaging Price Buy
SML0798 5mg $261 Buy
SML0798 25mg $916 Buy
CS-0003438 1mg $260 Buy
INB0005576 5MG $420.1 Buy
CS-0003438 5mg $780 Buy

Osanetant Chemical Properties,Uses,Production

Biochem/physiol Actions

Osanetant is a selective antagonist of neurokinin 3 receptor NK3. Neurokinins (tachykinins) are members of a family of at least three neuropeptides, substance P, neurokinin A, and neurokinin B (NKB), with each mediating their biological effects through binding to a preferred G-protein-coupled receptor termed NK1, NK2, or NK3, respectively. All three NK receptors are expressed in regions of the central nervous system that are related to emotion and cognition (i.e., amygdala and hippocampus) and have been linked to various degrees in psychiatric disorders. Neurokinin receptors, including NK3 receptors, are also expressed in the motor and sensory systems of the digestive tract. Osanetant was in clinical trials for both irritable bowel syndrome and schizophrenia.

Osanetant Preparation Products And Raw materials

Raw materials

Preparation Products

Osanetant Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33350 58
Nanjing JinruiJiuAn Biotechnology Co., Ltd. 025-58196018 800028039 sales@fartop.net China 2231 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
BOC Sciences -- info@bocsci.com USA 0 65
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44843 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 29778 58
Osanetant AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl- N-[1-[3-[(3R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-methylacetamide (R)-N-{{3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-methylacetamine SR142801 SR-142801 Osanetant AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl- N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide Osanetant >=98% (HPLC) 160492-56-8 C35H41Cl2N3O2