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Thalicarpine

Thalicarpine structure

CAS No.: 5373-42-2

Chemical Name:: Thalicarpine

Synonyms: Nsc68075;Aids002681;Aids-002681;Thalicarpine;Thaliblastine;(6aS)-9-[4,5-Dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl]methyl]phenoxy]-5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline;4H-Dibenzo[de,G]quinoline, 9-[4,5-dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]-5,6,6A,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6as)-;4H-Dibenzo(de,G)quinoline, 9-(4,5-dimethoxy-2-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-5,6,6A,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (S-(R*,R*))-

CBNumber:: CB31179887

Molecular Formula:: C41H48N2O8

Molecular Weight:: 696.83

MDL Number:: MFCD00866316

MOL File:: 5373-42-2.mol

MSDS File:: SDS

Last updated:2023-05-04 17:34:39

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Thalicarpine Properties

Melting point	160-161°
alpha	D25 +133° (c = 0.83 in methanol); D25 +89° (c = 0.88 in chloroform)
Boiling point	701.43°C (rough estimate)
Density	1.1544 (rough estimate)
refractive index	1.4670 (estimate)
pka	7.62±0.40(Predicted)
FDA UNII	8X1D791RF6
NCI Drug Dictionary	thalicarpine

Thalicarpine price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	API0012610	THALICARPINE 95.00%	5373-42-2	5MG	$498.49	2021-12-16	Buy

Product number	Packaging	Price	Buy
API0012610	5MG	$498.49	Buy

Thalicarpine Chemical Properties,Uses,Production

Description

A complex alkaloid, thaliblastine occurs in Thalictrum minus elatum and has been assigned the structure given on the basis of chemical and spectroscopic investigations. The alkaloid has marked antitumour activity but rapid administration of the base causes brachycardia, hypotension and inhibition of respiration in laboratory animals. Slow intravenous injection, however, produces none of these effects. Thaliblastine is cytotoxic to HEF and Sa9 cells in vitro.

Definition

ChEBI: Thalicarpine is a member of isoquinolines and a bisbenzylisoquinoline alkaloid.

References

Todorov, Damyanova,Dokl. Bolg. Akad. Nauk., 28, 709 (1975)

Thalicarpine Preparation Products And Raw materials

Raw materials

Preparation Products

Thalicarpine Suppliers

Global( 3)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21687	55
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.com	China	24246	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
TargetMol Chemicals Inc.	58

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4-METHOXY-3'-METHYLBIPHENYL Thalicarpine 4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)-

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Thalicarpine (6aS)-9-[4,5-Dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl]methyl]phenoxy]-5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline Thaliblastine 4H-Dibenzo(de,G)quinoline, 9-(4,5-dimethoxy-2-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-5,6,6A,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (S-(R*,R*))- 4H-Dibenzo[de,G]quinoline, 9-[4,5-dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]-5,6,6A,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6as)- Aids002681 Aids-002681 Nsc68075 5373-42-2 C41H48N2O8