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YL-939

YL-939 Structure
YL-939 structure
CAS No.
3023925-68-7
Chemical Name:
YL-939
Synonyms
YL-939;Imidazo[1,2-a]pyrazine, 8-(3,6-dihydro-2H-pyran-4-yl)-2-phenyl-6-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-
CBNumber:
CB313731657
Molecular Formula:
C25H26N6O
Molecular Weight:
426.51
MDL Number:
MOL File:
3023925-68-7.mol
Last updated:2025-10-28 16:00:23
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YL-939 Properties

Density 1.374±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility Acetonitrile: Slightly soluble: 0.1-1 mg/ml
DMSO: Slightly soluble: 0.1-1 mg/ml
Water: Slightly soluble: 0.1-1 mg/ml
pka 9.805±0.10(predicted)
form Solid
color Off-white to light yellow

YL-939 Chemical Properties,Uses,Production

Uses

YL-939 is a potent ferroptosis inhibitor. YL-939 inhibits ferroptosis by targeting the PHB2/ferritin/iron axis[1].

in vivo

YL-939 (3 mg/kg; i.p.; single injection) ameliorates liver damage in an Acetaminophen (APAP)-induced acute liver injury mode[1]l.

Animal Model:Acetaminophen (APAP)-induced male C57BL/6J mouse[1]
Dosage:3 mg/kg
Administration:Intraperitoneal injection; single injection
Result:Inhibited the cell death and inflammatory infiltration in the liver tissues of male C57BL/J6 mice that received APAP.

References

[1] Yang W, et, al. Non-classical ferroptosis inhibition by a small molecule targeting PHB2. Nat Commun. 2022 Dec 3;13(1):7473. DOI:10.1038/s41467-022-35294-2

YL-939 Preparation Products And Raw materials

Raw materials

Preparation Products

YL-939 Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19962 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4989 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5929 58
Cayman Chemical Company 800-364-9897 sales@caymanchem.com China 6838 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
ShangHai ChuanQian Chemcial Technique Centre 58
Nantong QuanYi Biotechnology Co., Ltd 58
Cayman Chemical Company 58

View Lastest Price from YL-939 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
YL-939 pictures 2025-10-27 YL-939
US $1190.00-916.00 / mg 10g TargetMol Chemicals Inc.
  • YL-939 pictures
  • YL-939
  • US $1190.00-916.00 / mg
  • TargetMol Chemicals Inc.
YL-939 Imidazo[1,2-a]pyrazine, 8-(3,6-dihydro-2H-pyran-4-yl)-2-phenyl-6-[1-(4-piperidinyl)-1H-pyrazol-4-yl]- 3023925-68-7