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LP-6

CAS No.
1629736-79-3
Chemical Name:
LP-6
Synonyms
LP-6;1H-Imidazole-2-butanamide, 4-(2,5-difluorophenyl)-N-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]-γ-[[[(3S,4R)-4-fluoro-3-pyrrolidinyl]methyl][(2S)-2-hydroxy-1-oxopropyl]amino]-β,β-dimethyl-1-(phenylmethyl)-, (γR)-
CBNumber:
CB314273613
Molecular Formula:
Molecular Weight:
694.74
MDL Number:
MOL File:
1629736-79-3.mol
Last updated:2025-04-18 09:52:03

LP-6 Properties

Boiling point 883.985±65.00 °C(Press: 760.00 Torr)(predicted)
Density 1.356±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 13.518±0.20(predicted)

LP-6 Chemical Properties,Uses,Production

Uses

LP-6 is a Drug-Linker Conjugates for ADC, and can be used for synthesis of ADCs. LP-6 consists of an Eg5 inhibitor and a linker[1].

References

[1] Karpov AS, et al. Discovery of Potent and Selective Antibody-Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization. ACS Med Chem Lett. 2019 Dec 3;10(12):1674-1679. DOI:10.1021/acsmedchemlett.9b00468

LP-6 Preparation Products And Raw materials

Raw materials

Preparation Products

LP-6 Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29547 58
Supplier Advantage
TargetMol Chemicals Inc. 58
LP-6 1H-Imidazole-2-butanamide, 4-(2,5-difluorophenyl)-N-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]-γ-[[[(3S,4R)-4-fluoro-3-pyrrolidinyl]methyl][(2S)-2-hydroxy-1-oxopropyl]amino]-β,β-dimethyl-1-(phenylmethyl)-, (γR)- 1629736-79-3