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[(S)-Cyclopropyl(phenyl)methyl]amine

CAS No.
321863-61-0
Chemical Name:
[(S)-Cyclopropyl(phenyl)methyl]amine
Synonyms
[(S)-Cyclopropyl(phenyl)methyl]amine;(S)-1-Cyclopropyl-1-phenylmethanamine;(S)-C-Cyclopropyl-C-phenyl-methylamine;Benzenemethanamine, α-cyclopropyl-, (αS)-;(alphaS)-alpha-Cyclopropylbenzenemethanamine
CBNumber:
CB32490079
Molecular Formula:
C10H13N
Molecular Weight:
147.22
MDL Number:
MOL File:
321863-61-0.mol

[(S)-Cyclopropyl(phenyl)methyl]amine Properties

Boiling point 234.7±9.0 °C(Predicted)
Density 1.082
pka 9.29±0.10(Predicted)

[(S)-Cyclopropyl(phenyl)methyl]amine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation CCH0031051 (1S)-CYCLOPROPYLPHENYLMETHYLAMINE 95.00% 321863-61-0 5MG $497.59 2021-12-16 Buy
American Custom Chemicals Corporation CCH0031051 (1S)-CYCLOPROPYLPHENYLMETHYLAMINE 95.00% 321863-61-0 1G $853.65 2021-12-16 Buy
Product number Packaging Price Buy
CCH0031051 5MG $497.59 Buy
CCH0031051 1G $853.65 Buy

[(S)-Cyclopropyl(phenyl)methyl]amine Chemical Properties,Uses,Production

Uses

[(S)-Cyclopropyl(phenyl)methyl]amine can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis

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A solution of (S)-2-amino-3-methyl-1,1-diphenylbutan-1-ol (47 mmoL 12 g) in THF (80 mL) was stirred at temperature below 30 °C. followed by slow addition of borane-tetrahydrofuran solution (1M, 95 mL). The tempera-ture was allowed to rise to room temperature over 2 h, The reaction mixture was then stirred at 0 °C. and the solution of pure anti-cyclopropyl(phenyl)methamine-benzyl oxime (19 mmol, 5 g), in THF (10 mL) was added. After stirring the mixture for 20 h at room temperature, the reaction mixture was cooled to 0 °C. and treated with hydrochloric acid (2N, 100 mL). The mixture was stirred for 16 h then basified at 0 °C. by addition of 35% sodium hydroxide (100 mL) followed by extraction with ethyl acetate. Extract washed with water and brine, dried over sodium sulfate and evaporated to dryness. Amine was purified by LC (BIOTAGE SPI purification system), using chloroform:methanol (gradient up to 25% of methanol) to give 2.1 g of (S)-cyclopropyl(phenyl)methanamine, yield 72%.

[(S)-Cyclopropyl(phenyl)methyl]amine Preparation Products And Raw materials

Raw materials

Preparation Products

[(S)-Cyclopropyl(phenyl)methyl]amine Suppliers

Global( 24)Suppliers
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CONIER CHEM AND PHARMA LIMITED
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Dayang Chem (Hangzhou) Co.,Ltd.
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GIHI CHEMICALS CO.,LIMITED
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Amadis Chemical Company Limited
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Shijiazhuang Lickon PharmaTech Co., Ltd. 0311-0311-85291771 13832391721 lickonpharm@hotmail.com China 974 58
LABTER PHARMATECH(BEIJING) CO.,LTD 010-56330744 18310155299 sales@labter.com.cn China 23339 55
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321863-61-0([(S)-Cyclopropyl(phenyl)methyl]amine)Related Search:

(alphaS)-alpha-Cyclopropylbenzenemethanamine [(S)-Cyclopropyl(phenyl)methyl]amine (S)-C-Cyclopropyl-C-phenyl-methylamine (S)-1-Cyclopropyl-1-phenylmethanamine Benzenemethanamine, α-cyclopropyl-, (αS)- 321863-61-0