ChemicalBook >> CAS DataBase List >>5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol
5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol
![5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol Structure](CAS/GIF/172152-53-3.gif)
- CAS No.
- 172152-53-3
- Chemical Name:
- 5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol
- Synonyms
- 5-(1H-pyrrol-1-yl)-1H-benzo[d]iMidazole-2-thiol;Ilaprazole Impurity A;Ilaprazole Intermediate 2;Enavogliflozin Impurity 21;Ilaprazole intermediate P-3;5-Pyrrol-1-yl-1H-benzoimidazole-2-thiol;5-(1H-Pyroll-1-yl)-2-Mercaptobenzimidazole;5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole;5-(1H-purrole-1-yl)-2-marcapto- benzimidazole;5-pyrrol-1-yl-1,3-dihydrobenzimidazole-2-thione
- CBNumber:
- CB32521216
- Molecular Formula:
- C11H9N3S
- Molecular Weight:
- 215.27
- MDL Number:
- MFCD15144909
- MOL File:
- 172152-53-3.mol
Last updated:2024-08-13 09:40:01
| Boiling point | 381.7±44.0 °C(Predicted) |
|---|---|
| Density | 1.40 |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.61±0.30(Predicted) |
| color | White to Pale Green |
| InChI | InChI=1S/C11H9N3S/c15-11-12-9-4-3-8(7-10(9)13-11)14-5-1-2-6-14/h1-7H,(H2,12,13,15) |
| InChIKey | YYXGYVYKGRUILQ-UHFFFAOYSA-N |
| SMILES | C1(=S)NC2=CC=C(N3C=CC=C3)C=C2N1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | CHM0390405 | 5-(1H-PYRROL-1-YL)-1H-BENZO[D]IMIDAZOLE-2-THIOL 95.00% | 172152-53-3 | 5MG | $504.94 | 2021-12-16 | Buy |
| Chemenu | CM162085 | 5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole 95% | 172152-53-3 | 5g | $777 | 2021-12-16 | Buy |
| Crysdot | CD11233680 | 5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol 95+% | 172152-53-3 | 5g | $831 | 2021-12-16 | Buy |
| AccelPharmtech | A7973 | 1,3-dihydro-5-(1H-pyrrol-1-yl)-2H-Benzimidazole-2-thione 97.00% | 172152-53-3 | 1G | $1740 | 2021-12-16 | Buy |
| AccelPharmtech | A7973 | 1,3-dihydro-5-(1H-pyrrol-1-yl)-2H-Benzimidazole-2-thione 97.00% | 172152-53-3 | 5G | $2960 | 2021-12-16 | Buy |
5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol Chemical Properties,Uses,Production
Uses
5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole is a pharmaceutical intermediate compound used in the synthesis of various drugs such as ilaprazole, gastric and ulcer drugs.
Synthesis
Water (100ml) and anhydrous sodium acetate (16.02g, 0.20mole) were added, and then 2-mercapto-5- aminobenzimidazole (32.27g, 0.20mole),2,5-dimethoxytetrahydrofuran (28.4g, 0.21mole), and acetic acid (100ml) were added. Then, stirring was carried out at 5O℃ for 4 hours. The resultant product was cooled to 50C, and tetrahydrofuran (420ml) was added. The mixture was neutralized with a sodium hydroxide aqueous solution, and water (130ml) was added to carry out layer- separation. Then, an organic layer was washed with a sodium hydroxide aqueous solution. The organic layer was dried by anhydrous magnesium sulfate and concentrated, and then crystallized by ethyl acetate and n-hexane to provide a final compound, that is 5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol. Yield: 35.7g (85%)
Synthesis of 5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol from 2,5-Dimethoxytetrahydrofuran and 5-Amino-2-benzimidazolethiol
5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol Preparation Products And Raw materials
Global( 197)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhuhai Hairuide Bioscience and Technology Co., Ltd | +8618928027945 | sales3@zhhairuide.com | China | 97 | 58 |
| Beri Pharma Co., Ltd. | +8613417710166 | sales@zhberi.com | China | 227 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18629 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9354 | 55 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2966 | 58 |
View Lastest Price from 5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-09-18 | 5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole
172152-53-3
|
US $0.00 / Kg/Drum | 1KG | 98%min | 10 tons | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2023-09-08 | 5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole
172152-53-3
|
US $0.00 / KG Ton | 1KG Ton | 99%+ | 2 tons/month | Zhuhai Hairuide Bioscience and Technology Co., Ltd | |
 |
2022-10-11 | 5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole
172152-53-3
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole
172152-53-3
- US $0.00 / Kg/Drum
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole
172152-53-3
- US $0.00 / KG Ton
- 99%+
- Zhuhai Hairuide Bioscience and Technology Co., Ltd
-
- 5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole
172152-53-3
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
172152-53-3(5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol)Related Search:
1,3-dihydro-5-(1H-pyrrol-1-yl)-2H-Benzimidazole-2-thione
5-pyrrol-1-yl-1,3-dihydrobenzimidazole-2-thione
5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole
2H-Benzimidazole-2-thione, 1,3-dihydro-5-(1H-pyrrol-1-yl)-
5-(1H-purrole-1-yl)-2-marcapto- benzimidazole
5-(1H-pyrrol-1-yl)-1H-benzo[d]iMidazole-2-thiol
Ilaprazole Intermediate 2
5-Pyrrol-1-yl-1H-benzoimidazole-2-thiol
Enavogliflozin Impurity 21
5- (1H pyrrolidine-1-yl) -2-mercaptobenzimidazole
5-(1H-Pyroll-1-yl)-2-Mercaptobenzimidazole
5-(1H-pyrrol-1-yl)-1H-benzo[d]imidazole-2(3H)-thione
Ilaprazole intermediate P-3
Ilaprazole Impurity A
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