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(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline

(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline structure

CAS No.: 180272-45-1

Chemical Name:: (1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline

Synonyms: Solifenacin Impurity 2;Solifenacin Impurity 42;(S)-quinuclidin-3-yl acetate;Solifenacin Related Compound 9;Solifenacin Succinate interMediate G;(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline;(R)-1-Phenyl-1,2,3,4-tetrhydroisoquinoline;(R)-1,2,3,4-Tetrahydro-1-phenylisoquinoline;(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline;(1R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline

CBNumber:: CB32565892

Molecular Formula:: C15H15N

Molecular Weight:: 209.29

MDL Number:: MFCD11858641

MOL File:: 180272-45-1.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

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(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline Properties

Melting point	78-79℃
Density	1.065
storage temp.	2-8°C
solubility	Chloroform (Slightly), Dichloromethane (Sparingly), DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Pale Beige

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	P2215	(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline	180272-45-1	200MG	$158	2024-03-01	Buy
TRC	P336925	(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline	180272-45-1	10g	$1455	2021-12-16	Buy
Ark Pharm	P000154177	(1R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline 98%	180272-45-1	25g	$343	2021-12-16	Buy
Biosynth Carbosynth	IP46848	(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline	180272-45-1	2g	$520	2021-12-16	Buy
Medical Isotopes, Inc.	48286	(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline	180272-45-1	25g	$625	2021-12-16	Buy

Product number	Packaging	Price	Buy
P2215	200MG	$158	Buy
P336925	10g	$1455	Buy
P000154177	25g	$343	Buy
IP46848	2g	$520	Buy
48286	25g	$625	Buy

(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline Chemical Properties,Uses,Production

Uses

(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is the counterpart to (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline, the latter enantiomer being a key intermediate in the preparation of Solifenacin (S676700), an antimuscarinic agent. Since (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is produced as a by-product, it has been suggested that it should be recycled in order to obtain the S enantiomer on a larger scale. (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is also used as a reagent to prepare quinuclidin-3-yl 1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives, compounds that act as muscarinic receptor antagonists.

(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline synthesis

Synthesis of (1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline from Phenylisoquinoline

(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

1-Phenyl-3,4-dihydroisoquinoline

(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline Suppliers

Global( 99)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hubei Jusheng Technology Co.,Ltd.	58
Standardpharm Co. Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
SIMAGCHEM CORP	58
LEAPCHEM CO., LTD.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58

View Lastest Price from (1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-12-31	(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline 180272-45-1	US $6.60 / KG	1KG	97%-99%	1kg-1000kg	Career Henan Chemical Co

(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline
180272-45-1
US $6.60 / KG
97%-99%
Career Henan Chemical Co

180272-45-1((1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline)Related Search:

3-QUINUCLIDINONE Solifenacin Related Compound 25 Solifenacin Impurity 1 1-Phenyl-3,4-dihydroisoquinoline 1-Phenyl-1,2,3,4-tetrahydro-isoquinoline

Ethyl (S)-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate Solifenacin succinate Solifenacin N-Oxide Solifenacin IMpurity (S)-(+)-3-Quinuclidinol

1-Azabicyclo[2.2.2]octan-3-ol, 3-acetate, (3R)- Solifenacin Related Compound 14 Solifenacin Related Compound 13 Dimethyl carbonate 4-(DICHLOROMETHYL)PYRIDINE HCL

Solifenacin Related Compound 18 Solifenacin Related Compound 29 3-Quinuclidinol

1of4

(1R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline (1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline (R)-1-Phenyl-1,2,3,4-tetrhydroisoquinoline Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl-, (1R)- Solifenacin Succinate interMediate G Solifenacin Impurity 2 (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline(W.S) (R)-1,2,3,4-Tetrahydro-1-phenylisoquinoline,99%e.e. TIANFU-CHEM (1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline (R)-1,2,3,4-Tetrahydro-1-phenylisoquinoline Solifenacin Related Compound 9 (1R)-1,2,3,4-Tetrahydro-1-phenyl-isoquinoline Solifenacin impurity 10/Solifenacin R Isomer/(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline Solifenacin Impurity 42 (S)-quinuclidin-3-yl acetate 180272-45-1