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YE-120

CAS No.
383124-82-1
Chemical Name:
YE-120
Synonyms
YE-120;2-[3-Cyano-5-(3,4-dichloro-phenyl)-4,5-dimethyl-5H-furan-2-ylidene]-malononitrile;2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile;Propanedinitrile, 2-[3-cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]-
CBNumber:
CB32652554
Molecular Formula:
C16H9Cl2N3O
Molecular Weight:
330.17
MDL Number:
MOL File:
383124-82-1.mol
Last updated:2023-06-30 15:45:59

YE-120 Properties

Boiling point 419.1±45.0 °C(Predicted)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble to 100 mM in DMSO
form Powder

YE-120 price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29720 YE 120 383124-82-1 1mg $62 2024-03-01 Buy
Cayman Chemical 29720 YE 120 383124-82-1 5mg $180 2024-03-01 Buy
Tocris 4457 YE120 ≥98%(HPLC) 383124-82-1 10 $210 2021-12-16 Buy
Tocris 4457 YE120 ≥98%(HPLC) 383124-82-1 50 $846 2021-12-16 Buy
TRC Y100700 YE-120 383124-82-1 100mg $1175 2021-12-16 Buy
Product number Packaging Price Buy
29720 1mg $62 Buy
29720 5mg $180 Buy
4457 10 $210 Buy
4457 50 $846 Buy
Y100700 100mg $1175 Buy

YE-120 Chemical Properties,Uses,Production

Uses

YE-120 is a GPR35 agonist (EC50 = 32 nM in DMR assays). YE-120 also displays partial agonist activity in a β-arrestin translocation assay (EC50 = 10.2 μM). GPR35 is a Class A, rhodopsin-like G protein-coupled receptor which is predominantly expressed in immune and gastrointestinal tissue, with notable expression in the ileum (rat and human GPR35), the spleen (rat and murine GPR35) and the pancreas (human GPR35).

storage

Store at -20°C

436097-03-9
109-77-3
383124-82-1
Synthesis of YE-120 from 3-(3,4-Dichlorophenyl)-3-hydroxy-2-butanone and Malononitrile

YE-120 Preparation Products And Raw materials

Raw materials

Preparation Products

YE-120 Suppliers

Global( 33)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 56032 58
BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8618 58
YE-120 2-[3-Cyano-5-(3,4-dichloro-phenyl)-4,5-dimethyl-5H-furan-2-ylidene]-malononitrile 2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile Propanedinitrile, 2-[3-cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]- 383124-82-1 C16H9Cl2N3O