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Hydroxy-PEG4-t-butyl ester

CAS No.
518044-32-1
Chemical Name:
Hydroxy-PEG4-t-butyl ester
Synonyms
OH-PEG4-TBA;HO-PEG4-TBA;HO-PEG4-COOtBu;PEG5-t-butly ester;HO-PEG4-CH2CH2COOTBU;OH-PEG4-CH2CH2COOtBu;Hydroxy-PEG4-(CH2)2-Boc;HO-PEG4 tert-Butyl Ester;Hydroxy-PEG4-t-butly ester;tert-Butyl PEG4 propanoate
CBNumber:
CB32747166
Molecular Formula:
C15H30O7
Molecular Weight:
322.39
MDL Number:
MFCD11041117
MOL File:
518044-32-1.mol
MSDS File:
SDS
Last updated:2024-03-25 20:41:16

Hydroxy-PEG4-t-butyl ester Properties

Boiling point 406.8±35.0 °C(Predicted)
Density 1.04746 g/mL
refractive index n/D 1.4492
storage temp. 2-8°C
solubility Soluble in Water, DCM
form liquid
pka 14.36±0.10(Predicted)
color Colorless to Light yellow to Light orange

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2918999090
NFPA 704
1
0 0

Hydroxy-PEG4-t-butyl ester price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 902586 Hydroxy-PEG4-t-butyl ester 518044-32-1 1g $274 2024-03-01 Buy
Sigma-Aldrich 902586 Hydroxy-PEG4-t-butyl ester 518044-32-1 250mg $74.6 2023-06-20 Buy
TCI Chemical B5901 PEG5-Carboxylic Acid tert-Butyl Ester 518044-32-1 1G $111 2024-03-01 Buy
TCI Chemical B5901 PEG5-Carboxylic Acid tert-Butyl Ester 518044-32-1 5G $376 2024-03-01 Buy
TRC H936410 Hydroxy-Peg4-T-ButlyEster 518044-32-1 500mg $155 2021-12-16 Buy
Product number Packaging Price Buy
902586 1g $274 Buy
902586 250mg $74.6 Buy
B5901 1G $111 Buy
B5901 5G $376 Buy
H936410 500mg $155 Buy

Hydroxy-PEG4-t-butyl ester Chemical Properties,Uses,Production

Description

Hydroxy-PEG4-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG4-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

Hydroxy-PEG4-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 116)Suppliers
Supplier Tel Email Country ProdList Advantage
9i LLC
+18039569191 MWan@NiNeiLab.com United States 418 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Chengdu Pukang Biotechnology Co., Ltd
028-82550498 export@pu-kang.com CHINA 210 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Wuhan Borenpharm Co., Ltd
027-65563561 18717150066 3207347307@qq.com CHINA 1238 58
WinWin Chemical CO., Limited
+86-0577-64498589 +8615325081899 sales@win-winchemical.com China 14145 58

View Lastest Price from Hydroxy-PEG4-t-butyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Hydroxy-PEG4-t-butyl ester pictures 2024-03-25 Hydroxy-PEG4-t-butyl ester
518044-32-1
US $0.00 / g 25g >98.00% 25g Xian confluore Biological Technology Co., Ltd.
Hydroxy-PEG-5-t-butyl ester pictures 2019-12-23 Hydroxy-PEG-5-t-butyl ester
518044-32-1
US $1.00 / g 1g 99% 1000KGS Career Henan Chemical Co
HO-PEG4-CH2CH2COOTBU Hydroxy-PEG-5-t-butyl ester PEG5-t-butly ester Hydroxy-PEG4-t-butly ester OH-PEG4-CH2CH2COOtBu OH-PEG4-TBA HO-PEG4-COOtBu t-Butyl 3-Hydroxy(PEG4)propoinate HYDROXY-PEG4-PROPANOIC ACID T-BUTYL ESTER tert-Butyl 1-Hydroxy-3,6,9,12-tetraoxapentadecan-15-oate tert-butyl 3-(2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)propanoate Hydroxy-PEG4-(CH2)2-Boc 4,7,10,13-Tetraoxapentadecanoic acid, 15-hydroxy-, 1,1-dimethylethyl ester tert-Butyl PEG4 propanoate PEG5-Carboxylic Acid tert-Butyl Ester 1-Hydroxy-3,6,9,12-tetraoxapentadecan-15-oic Acid tert-Butyl Ester HO-PEG4 tert-Butyl Ester Hydroxy-dPEG4-t-butyl ester HO-PEG4-CH2CH2COOtBu /4,7,10,13-Tetraoxapentadecanoic acid, 15-hydroxy-, 1,1-dimethylethyl ester HO-PEG4-TBA 518044-32-1 peg