5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE
- CAS No.
- 3031-94-5
- Chemical Name:
- 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE
- Synonyms
- ZMP;acadesine 5'-monophosphate;AICA-Riboside, 5′-Phosphate;5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE;NSC 283955;NSC 292227;AICAR-5'-MP;Acaribonucleotide;AICAR-5'-MP / ZMP;aicaribonucleotide
- CBNumber:
- CB3466890
- Molecular Formula:
- C9H15N4O8P
- Molecular Weight:
- 338.21
- MDL Number:
- MFCD00057264
- MOL File:
- 3031-94-5.mol
- MSDS File:
- SDS
Melting point | 198-202°C dec. |
---|---|
Boiling point | 845.3±75.0 °C(Predicted) |
Density | 2.30±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMSO (Slightly, Heated, Sonicated), Methanol (Slightly), Water (Slightly) |
pka | 1.86±0.10(Predicted) |
form | White to light pink solid |
color | White to Pink |
optical activity | [α]/D -69.0±3.0°, c = 0.1 in sodium bicarbonate |
Stability | Hygroscopic |
InChIKey | UDYDDOATBNVEES-UUOKFMHZSA-N |
FDA UNII | F0X88YW0YK |
SAFETY
Risk and Safety Statements
Safety Statements | 24/25 |
---|---|
WGK Germany | 3 |
HS Code | 29349990 |
5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE price More Price(15)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | A1393 | 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate ≥93% | 3031-94-5 | 50mg | $664 | 2024-03-01 | Buy |
Sigma-Aldrich | 123041 | AICA-Riboside, 5?-Phosphate | 3031-94-5 | 25mg | $265 | 2024-03-01 | Buy |
Sigma-Aldrich | 06595 | 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate analytical standard | 3031-94-5 | 25mg | $744 | 2024-03-01 | Buy |
Sigma-Aldrich | A1393 | 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate ≥93% | 3031-94-5 | 100mg | $1230 | 2024-03-01 | Buy |
TRC | A611705 | 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate | 3031-94-5 | 500mg | $1390 | 2021-12-16 | Buy |
5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE Chemical Properties,Uses,Production
Chemical Properties
White Powder With Pink Tinge.
Uses
AICAR monophosphate is a 5′′-phosphorylated analog of cell permeable AICAR that mimics AMP. AICAR is an adenosine monophophate (AMP)-activated protein kinase (AMPK) activator/agonist.
Definition
ChEBI: AICA ribonucleotide is a 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative. It has a role as a cardiovascular drug, a plant metabolite, a human metabolite, an Escherichia coli metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is a 1-(phosphoribosyl)imidazolecarboxamide and an aminoimidazole. It is functionally related to an acadesine. It is a conjugate acid of a 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-).
General Description
5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate (AICAR monophosphate) is an intermediate metabolite in the purine de novo synthesis pathway and a potent activator of the human AMP-activated protein kinase (AMPK) activity in vitro. It can play an important regulatory role.
Biochem/physiol Actions
A 5′-phosphorylated analog of cell permeable AICAR that mimics adenosine monophosphate (AMP). It is an AMP-activated protein kinase (AMPK) activator.In humans, 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate (AICAR) is found to be accumulated in numerous metabolic diseases. It can increase the endurance of sedentary mice. AICAR exhibits antiproliferative effects. It can induce apoptosis of aneuploid cells.
5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE Preparation Products And Raw materials
Raw materials
Preparation Products
5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 | market02@senwayer.com | China | 905 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3465 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 24099 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15394 | 58 |
BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
View Lastest Price from 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-18 | AICAR
3031-94-5
|
US $0.00 / g | 1g | 99% min | 20 tons | Wuhan Senwayer Century Chemical Co.,Ltd | ||
2022-10-14 | 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE
3031-94-5
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
- AICAR
3031-94-5
- US $0.00 / g
- 99% min
- Wuhan Senwayer Century Chemical Co.,Ltd
- 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE
3031-94-5
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.