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BPKDi

BPKDi structure

CAS No.: 1201673-28-0

Chemical Name:: BPKDi

Synonyms: BPKDi;[2,4'-Bipyridine]-4-carboxamide, 2'-(cyclohexylamino)-6-(1-piperazinyl)-

CBNumber:: CB34718593

Molecular Formula:: C21H28N6O

Molecular Weight:: 380.49

MDL Number:: MFCD28160405

MOL File:: 1201673-28-0.mol

Last updated:2023-05-21 10:59:17

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BPKDi Properties

Boiling point	633.1±55.0 °C(Predicted)
Density	1.226±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMSO: soluble
form	A solid
pka	14.86±0.50(Predicted)

BPKDi price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Axon Medchem	Axon2798	BPKDi 99%	1201673-28-0	5mg	$170.5	2021-12-16	Buy
Axon Medchem	Axon2798	BPKDi 99%	1201673-28-0	25mg	$605	2021-12-16	Buy

Product number	Packaging	Price	Buy
Axon2798	5mg	$170.5	Buy
Axon2798	25mg	$605	Buy

BPKDi Chemical Properties,Uses,Production

Biological Activity

BPKDi is an inhibitor of protein kinase D (PKD; IC50s = 1, 9, and 1 nM for PKD1, PKD2, and PKD3, respectively).1 It is selective for PKD over PKCδ and PKCε, as well as over a panel of additional calcium/calmodulin-dependent protein kinase (CaMK) superfamily members, at 1 μM. It inhibits phenylephrine-induced phosphorylation and nuclear export of histone deacetylase 4 (HDAC4) and HDAC5 in, as well reduces phenylephrine-induced hypertrophy of, isolated neonatal rat ventricular myocytes when used at a concentration of 1 μM.

References

1.Monovich, L., Vega, R.B., Meredith, E., et al.A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinaseFEBS Lett.584(3)631-637(2010)

BPKDi Preparation Products And Raw materials

Raw materials

Preparation Products

BPKDi Suppliers

Global( 12)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
ATK CHEMICAL COMPANY LIMITED	3429815786 13301662590	sales@atkchemical.com	China	10006	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
ShangHai ChuanQian Chemcial Technique Centre	15869524721	3525679403@qq.com	China	3697	58
Jinan Jiuli Biotechnology Co. , Ltd.	2717893647 14768611851	486064515@qq.com	China	978	58
ChemeGen 中国	18818260767	sales@chemegen.com	China	6975	58
Beijing Biocreative Technology Co., Ltd.	15522676233	3007606172@qq.com	China	1249	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24024	58
Suzhou Zhixin Biotechnology Co., Ltd.	0512-65118909 15162312715	sales@szzxbio.com	China	2981	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4030	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
ATK CHEMICAL COMPANY LIMITED	55
Shanghai EFE Biological Technology Co., Ltd.	58
ShangHai ChuanQian Chemcial Technique Centre	58
Jinan Jiuli Biotechnology Co. , Ltd.	58
ChemeGen 中国	58
Beijing Biocreative Technology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Suzhou Zhixin Biotechnology Co., Ltd.	58
Nantong QuanYi Biotechnology Co., Ltd	58

BPKDi [2,4'-Bipyridine]-4-carboxamide, 2'-(cyclohexylamino)-6-(1-piperazinyl)- 1201673-28-0