Diisopropyl 2,2-dihydroxymalonate

CAS No.
70841-85-9
Chemical Name:
Diisopropyl 2,2-dihydroxymalonate
Synonyms
Diisopropyl 2,2-dihydroxymalonate;Propanedioic acid, 2,2-dihydroxy-, 1,3-bis(1-methylethyl) ester
CBNumber:
CB34846416
Molecular Formula:
C9H16O6
Molecular Weight:
220.22
MDL Number:
MOL File:
70841-85-9.mol

Diisopropyl 2,2-dihydroxymalonate Properties

Melting point 60 °C
Boiling point 290.7±35.0 °C(Predicted)
Density 1.224±0.06 g/cm3(Predicted)
pka 8.75±0.50(Predicted)

Diisopropyl 2,2-dihydroxymalonate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 902764 Diisopropyl 2,2-dihydroxymalonate ≥95% 70841-85-9 1G $83.6 2023-06-20 Buy
Sigma-Aldrich 902764 Diisopropyl 2,2-dihydroxymalonate ≥95% 70841-85-9 10G $500 2023-06-20 Buy
Product number Packaging Price Buy
902764 1G $83.6 Buy
902764 10G $500 Buy

Diisopropyl 2,2-dihydroxymalonate Chemical Properties,Uses,Production

Uses

As demonstrated by Laszlo Kürti′s lab, the sterically hindered di-isopropyl keto malonate hydrate (and 902594) are excellent N-umpolung reagents for both aliphatic and aromatic primary amines via a simple condensation reaction. The steric hindrance in ester moiety allows the preparation of the corresponding iminomalonates in high yield and lends these imines sufficient hydrolytic stability during the purification process. The N-alkyl as well as N-aryl iminomalonates act as singly N-electrophilic reagents towards strong C-nucleophiles such as alkyl- and arylmetals (e.g., Grignard reagents). Thus, unsymmetrical secondary amines may be readily preapred at low temperatures and in the absence of transition metal catalysts.

Diisopropyl 2,2-dihydroxymalonate Preparation Products And Raw materials

Raw materials

Preparation Products

Diisopropyl 2,2-dihydroxymalonate Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Diisopropyl 2,2-dihydroxymalonate Propanedioic acid, 2,2-dihydroxy-, 1,3-bis(1-methylethyl) ester 70841-85-9