ChemicalBook >> CAS DataBase List >>E3 Ligase Ligand-Linker Conjugates 58
E3 Ligase Ligand-Linker Conjugates 58
- CAS No.
- 2172820-14-1
- Chemical Name:
- E3 Ligase Ligand-Linker Conjugates 58
- Synonyms
- VH032-PEG5-COOH;VH 032 amide-PEG5-acid;(S,R,S)-AHPC-PEG5-COOH;VHL Ligand-Linker Conjugates 16;E3 Ligase Ligand-Linker Conjugates 58;L-Prolinamide, N-(18-carboxy-1-oxo-4,7,10,13,16-pentaoxaoctadec-1-yl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;(S)-21-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-22,22-dimethyl-19-oxo-4,7,10,13,16-pentaoxa-20-azatricosan-1-oic acid;1-{[(2S)-1-[(2S,4R)-4-hydroxy-2-({[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}carbamoyl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl}-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
- CBNumber:
- CB36127045
- Molecular Formula:
- C36H54N4O11S
- Molecular Weight:
- 750.9
- MDL Number:
- MFCD32693900
- MOL File:
- 2172820-14-1.mol
Last updated:2024-07-02 08:55:06
E3 Ligase Ligand-Linker Conjugates 58 Chemical Properties,Uses,Production
Biological Activity
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology[1].
storage
Store at -20°C
References
[1]. Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.
E3 Ligase Ligand-Linker Conjugates 58 Preparation Products And Raw materials
Raw materials
Preparation Products
E3 Ligase Ligand-Linker Conjugates 58 Suppliers
Global( 17)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32024 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7887 | 56 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1386 | 58 |
Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49312 | 58 |
Shanghai Haohong Pharmaceutical Co., Ltd. | 4008210725 4008210725 | malulu@leyan.com | China | 54986 | 58 |
Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8617 | 58 |
Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 | czbjpharma@126.com | China | 18478 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24649 | 58 |
E3 Ligase Ligand-Linker Conjugates 58
(S,R,S)-AHPC-PEG5-COOH
VH032-PEG5-COOH
VHL Ligand-Linker Conjugates 16
L-Prolinamide, N-(18-carboxy-1-oxo-4,7,10,13,16-pentaoxaoctadec-1-yl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
VH 032 amide-PEG5-acid
(S)-21-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-22,22-dimethyl-19-oxo-4,7,10,13,16-pentaoxa-20-azatricosan-1-oic acid
1-{[(2S)-1-[(2S,4R)-4-hydroxy-2-({[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}carbamoyl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl}-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
2172820-14-1
C36H54N4O11S