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ChemicalBook >> CAS DataBase List >>Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Structure
Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- structure
CAS No.
2360527-40-6
Chemical Name:
Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
Synonyms
Thalidomide-O-amido-C5-NH2;Thalidomide-O-amide-C5-NH2;N-(5-aminopentyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide;N-(5-aminopentyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide;Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
CBNumber:
CB38252129
Molecular Formula:
C20H24N4O6
Molecular Weight:
416.43
MDL Number:
MFCD32666632
MOL File:
2360527-40-6.mol
Last updated:2025-04-18 09:52:10
Product description Number Pack Size Price
Thalidomide-O-amido-C5-NH2 027605 001 $550
Thalidomide-O-amido-C5-NH2 027605 002 $950
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Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Properties

Boiling point 757.3±60.0 °C(Predicted)
Density 1.368±0.06 g/cm3(Predicted)
pka 10.68±0.40(Predicted)

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
DC Chemicals 027605 Thalidomide-O-amido-C5-NH2 2360527-40-6 001 $550 2021-12-16 Buy
DC Chemicals 027605 Thalidomide-O-amido-C5-NH2 2360527-40-6 002 $950 2021-12-16 Buy
Product number Packaging Price Buy
027605 001 $550 Buy
027605 002 $950 Buy

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Chemical Properties,Uses,Production

Uses

Thalidomide-O-amide-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

References

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Preparation Products And Raw materials

Raw materials

Preparation Products

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanxi Tihondan Pharmaceutical Technology Co., Ltd 		+8618235132063 sales@tihondan.com China 3767 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42056 58
SuZhou Medinoah Co.,LTD. 0512-69561983 13914027025 zhang_q@medinoah.com China 3811 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1615 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054; trendseenbio@gmail.com China 9069 58
Shanghai Easy CDMO Co.,Ltd 021-61734564 13854185395; info@easycdmo.com China 10024 58
Abosyn 0512-69561983 13914027025 he_qf@medinoah.com China 3001 58
Supplier Advantage
Shanxi Tihondan Pharmaceutical Technology Co., Ltd 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
SuZhou Medinoah Co.,LTD. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Shanghai Easy CDMO Co.,Ltd 58
Abosyn 58

2360527-40-6(Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-)Related Search:

E3 Ligase Ligand-Linker Conjugates 24 (TFA) N-(5-Aminopentyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride E3 Ligase Ligand-Linker Conjugates 21 E3 Ligase Ligand-Linker Conjugates 19 Thalidomide-O-amido-C4-NH2 hydrochloride
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Thalidomide-linker 15 Thalidomide-O-amido-C8-NH2 hydrochloride Thalidomide-O-amido-PEG4-azide Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride
Thalidomide-linker 14 Thalidomide-linker 13 N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide E3 Ligase Ligand-Linker Conjugates 20

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Thalidomide-O-amide-C5-NH2 Thalidomide-O-amido-C5-NH2 Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- N-(5-aminopentyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide N-(5-aminopentyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide 2360527-40-6