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Thalidomide-O-amido-C4-NH2 hydrochloride

Thalidomide-O-amido-C4-NH2 hydrochloride Structure
Thalidomide-O-amido-C4-NH2 hydrochloride structure
CAS No.
2245697-86-1
Chemical Name:
Thalidomide-O-amido-C4-NH2 hydrochloride
Synonyms
Thalidomide-linker 3;-oxyacetamide-alkylC4-amine;Thalidomide-O-amido-C4-NH2 hydrochloride;N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
CBNumber:
CB66127046
Molecular Formula:
C19H23ClN4O6
Molecular Weight:
438.87
MDL Number:
MFCD31656719
MOL File:
2245697-86-1.mol
Last updated:2025-04-18 09:52:30
Product description Number Pack Size Price
N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamidehydrochloride 95% 6591788 1g $1250
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Thalidomide-O-amido-C4-NH2 hydrochloride Properties

storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

HS Code  2933998090

Thalidomide-O-amido-C4-NH2 hydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
A1 Biochem Labs 6591788 N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamidehydrochloride 95% 2245697-86-1 1g $1250 2021-12-16 Buy
Product number Packaging Price Buy
6591788 1g $1250 Buy

Thalidomide-O-amido-C4-NH2 hydrochloride Chemical Properties,Uses,Production

Uses

Thalidomide-O-amido-C4-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins withPicomolar Cellular Potencies and Capable of Achieving Tumor Regression.J Med Chem. 2018 Jan 25;61(2):462-481. DOI:10.1021/acs.jmedchem.6b01816
[2] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.

Thalidomide-O-amido-C4-NH2 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Thalidomide-O-amido-C4-NH2 hydrochloride Suppliers

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd 		+8618235132063 sales@tihondan.com China 3767 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42056 58
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 1924344760@confluore.cn China 2997 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7778 56
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4952 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Xian confluore Biological Technology Co., Ltd. 		58
Aladdin Scientific 		58
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai Biochempartner Co.,Ltd 62
Xi'an Confluore Biological Technology Co., Ltd. 58

View Lastest Price from Thalidomide-O-amido-C4-NH2 hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Thalidomide-O-amido-C4-NH2 hydrochloride pictures 2025-06-07 Thalidomide-O-amido-C4-NH2 hydrochloride
2245697-86-1
 US $0.00 / mg 100mg >98.00% 100mg Xian confluore Biological Technology Co., Ltd.

2245697-86-1(Thalidomide-O-amido-C4-NH2 hydrochloride)Related Search:

N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide Thalidomide-O-C6-NH2 Thalidomide-O-C6-NH2 TFA Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Thalidomide-O-amido-C3-NH2 (TFA)
1H-Isoindole-1,3(2H)-dione, 4-[2-(2-aminoethoxy)ethoxy]-2-(2,6-dioxo-3-piperidinyl)- Cereblon Ligand 1 E3 Ligase Ligand-Linker Conjugates 21 E3 Ligase Ligand-Linker Conjugates 19 Thalidomide-O-PEG4-Propargyl
Thalidomide-linker 10 Acetamide, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl- Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Thalidomide-O-amido-C8-NH2 hydrochloride Thalidomide-O-PEG4-Boc
tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate Thalidomide-linker 13 E3 Ligase Ligand-Linker Conjugates 24 (TFA)

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Thalidomide-O-amido-C4-NH2 hydrochloride -oxyacetamide-alkylC4-amine Thalidomide-linker 3 N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride 2245697-86-1