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N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Structure
N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride structure
CAS No.
58934-46-6
Chemical Name:
N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride
Synonyms
Nsc310411;Lorcainide HCl;EINECS 261-504-6;Isocainide hydrochloride;LORCAINIDE HYDROCHLORIDE;4'-Chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide monohydrochloride;N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride;N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride USP/EP/BP;Benzeneacetamide, N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]-, monohydrochloride
CBNumber:
CB3904853
Molecular Formula:
C22H28Cl2N2O
Molecular Weight:
407.37652
MDL Number:
MOL File:
58934-46-6.mol
Last updated:2023-04-23 13:52:06
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N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Properties

Melting point 263°
storage temp. -20°C
solubility Soluble in DMSO (up to 20 mg/ml), in Water (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml).
form White solid.
color Powder
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO, distilled water or ethanol may be stored at -20°C for up to 1 month
FDA UNII 1T1S98ONM1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312a-P330-P501a

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J67098 Lorcainide hydrochloride, 98% 58934-46-6 10mg $126 2021-12-16 Buy
American Custom Chemicals Corporation HCH0041839 N-(4-CHLOROPHENYL)-2-PHENYL-N-(1-PROPAN-2-YL-3,4,5,6-TETRAHYDRO-2H-PYRIDIN-4-YL)ACETAMIDE CHLORIDE 95.00% 58934-46-6 5MG $500.72 2021-12-16 Buy
Product number Packaging Price Buy
J67098 10mg $126 Buy
HCH0041839 5MG $500.72 Buy

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Chemical Properties,Uses,Production

Description

Lorcainide hydrochloride (58934-46-6) is a voltage-gated Na+?channel blocker.1?Protects murine cultured cortical neurons from injury induced by oxygen-glucose deprivation.2?Acts at the ouabain binding site of guinea pig cardiac Na+/K+?ATPase and inhibits the enzyme (IC50?= 34 μM).3

Uses

Cardiac depressant (anti-arrhythmic).

References

1) Sheldon?et al.?(1989),?Antiarrhythmic drugs and the cardiac sodium channel: current models; Clin. Chem.,?35?748 2) Lynch?et al.?(1995),?Sodium channel clockers reduce oxygen-glucose deprivation-induced cortical neuronal injury when combined with glutamate receptor antagonists; J. Pharmacol. Exp. Ther.,?273?554 3) Almotrefi?et al. (1999),?Class I antiarrhythmic drug effects on ouabain binding to guinea pig cardiac Na+ -K+ ATPase; Can. J. Physiol. Pharmacol.,?77?866

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 9126 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24018 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Aladdin Scientific 		58
Shanghai EFE Biological Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58

58934-46-6(N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride)Related Search:

N-ETHYL-N-ISOPROPYLANILINE N,N-Dimethylpiperidin-4-amine 1,3-Propanediamine,N3,N3-diethyl-1-phenyl- 1,3-DIAMINOPROPANE DIHYDROCHLORIDE 4-(dimethylammonio)piperidinium dichloride
4-Aminopiperidine dihydrochloride N,N,N',N'-TETRAMETHYL-1,3-BUTANEDIAMINE 2,N-DIPHENYLACETAMIDE 4-ACETAMIDOPIPERIDINE 1-Methyl-4-(methylamino)piperidine
N-(1-METHYLPIPERIDIN-4-YL)ANILINE 1,3-Propanediamine,N3,N3-dimethyl-1-phenyl- N-Phenyl-N-(4-piperidinyl)propanamide admixture with HCl salt 1-ISOPROPYL-PIPERIDIN-4-YLAMINE Lorcainide
N-METHYL-N-4-PIPERIDINYLACETAMIDE 1-methyl-N-(2-phenylethyl)piperidin-4-amine N,N-DIMETHYL-2-PHENYLACETAMIDE

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N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride LORCAINIDE HYDROCHLORIDE Isocainide hydrochloride 4'-Chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide monohydrochloride Benzeneacetamide, N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]-, monohydrochloride Nsc310411 N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride USP/EP/BP Lorcainide HCl EINECS 261-504-6 58934-46-6 C22H28Cl2N2O