ChemicalBook >> CAS DataBase List >>Ametantrone
Ametantrone
- CAS No.
- 64862-96-0
- Chemical Name:
- Ametantrone
- Synonyms
- HAQ;CS-1411;NSC 290813;NSC 196473;NSC-287513;Ametantrone;Ametantrone, >=98%;ametantrone diacetate.;AMetantrone(NSC 196473);1,4-BIS(2-(2-HYDROXYETHYLAMINO)ETHYLAMINO)ANTHRACENE-9,10-DIOL
- CBNumber:
- CB41177996
- Molecular Formula:
- C22H28N4O4
- Molecular Weight:
- 412.48
- MDL Number:
- MFCD00723741
- MOL File:
- 64862-96-0.mol
- MSDS File:
- SDS
Last updated:2023-05-21 10:59:17
| Melting point | 156-158 °C |
|---|---|
| Boiling point | 531.92°C (rough estimate) |
| Density | 1.2344 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | Store at -20°C |
| solubility | DMSO: soluble |
| form | A crystalline solid |
| pka | 14.47±0.10(Predicted) |
| FDA UNII | PNT6041ST1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
Ametantrone price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22924 | Ametantrone | 64862-96-0 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 22924 | Ametantrone | 64862-96-0 | 5mg | $183 | 2024-03-01 | Buy |
| Cayman Chemical | 22924 | Ametantrone | 64862-96-0 | 10mg | $341 | 2024-03-01 | Buy |
| AK Scientific | 0251CA | Ametantrone | 64862-96-0 | 1mg | $147 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009086 | AMETANTRONE 95.00% | 64862-96-0 | 0.1G | $489.5 | 2021-12-16 | Buy |
Ametantrone Chemical Properties,Uses,Production
Description
Ametantrone is an inhibitor of topoisomerase II. It induces double-strand breaks in SV40 DNA in the presence, but not absence, of topoisomerase II and induces single-strand breaks in DNA in NCI H187 cells. It also induces interstrand DNA cross-links in HeLa S3 cells at a minimum concentration of 4.1 μM. Ametantrone is cytotoxic to NCI H187 and HL-60 cells (IC50s = 112 and 0.44 μM, respectively). It inhibits tumor growth in a Ridgway osteogenic sarcoma mouse model when administered at a dose of 5 mg/kg, however, it increases tumor growth in mouse models of mammary adenocarcinoma and colon adenocarcinoma 11a.
Ametantrone Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 60)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2784 | 58 |
View Lastest Price from Ametantrone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | Ametantrone
64862-96-0
|
US $0.50 / g | 1g | 98%min | 10g,100g,1kg | Career Henan Chemical Co |
-
- Ametantrone
64862-96-0
- US $0.50 / g
- 98%min
- Career Henan Chemical Co
64862-96-0(Ametantrone)Related Search:
Ametantrone
1,4-Bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthraquinone
HAQ
NSC-287513
NSC 196473
NSC 290813
AMetantrone(NSC 196473)
1,4-BIS(2-(2-HYDROXYETHYLAMINO)ETHYLAMINO)ANTHRACENE-9,10-DIOL
Ametantrone, >=98%
9,10-Anthracenedione,1,4-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-
CS-1411
ametantrone diacetate.
CI-881;NSC 196473;NSC 287513;NSC-196473;NSC-287513;AMETANTRONE DIACETATE.
64862-96-0