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Drotebanol

CAS No.
3176-03-2
Chemical Name:
Drotebanol
Synonyms
Metebanyl;Drotebanol;oxymetebanol;Oxymethebanol;LCAHPIFLPICNRW-SVYNMNNPSA-N;Dihydro-14-hydroxy-4-O-methyl-6b-thebainol;Dihydro-14-hydroxy-4-O-Methyl-6β-thebainol;3,4-Dimethoxy-17-methylmorphinan-6β,14-diol;3,4-Dimethoxy-17-methylmorphinan-6β,14β-diol;Dihydro-14-hydroxy-6b-thebainol 4-methyl ether
CBNumber:
CB41178584
Molecular Formula:
C19H27NO4
Molecular Weight:
333.42
MDL Number:
MOL File:
3176-03-2.mol
Last updated:2023-05-15 10:43:23

Drotebanol Properties

Melting point 165.5-166.5°
Boiling point 470.38°C (rough estimate)
Density 1.1618 (rough estimate)
refractive index 1.5180 (estimate)
solubility Chloroform (Slightly), Methanol (Slightly)
pka 13.83±0.40(Predicted)
form A solid
FDA UNII 7RS2Q8MCK8

SAFETY

Risk and Safety Statements

Toxicity LD50 in mice (mg/kg): 1300 orally, 1150 s.c., 91 i.v. (Kobayashi)
DEA Controlled Substances CSCN: 9335
CSA SCH: Schedule I
NARC: Yes

Drotebanol Chemical Properties,Uses,Production

Uses

An antitussive. Controlled substance (opium derivative).

Definition

ChEBI: Oxymetebanol is an organic molecular entity.

Safety Profile

Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion. An antitussive agent. When heated to decomposition it emits toxic fumes of NOx.

Drotebanol Preparation Products And Raw materials

Raw materials

Preparation Products

Drotebanol 6b,14-Dihydroxy-3,4-dimethoxy-N-methylmorphinan Dihydro-14-hydroxy-4-O-methyl-6b-thebainol Dihydro-14-hydroxy-6b-thebainol 4-methyl ether Metebanyl Morphinan, 6b,14-dihydroxy-3,4-dimethoxy-N-methyl- (7CI) Morphinan-6,14-diol, 3,4-dimethoxy-17-methyl-, (6b)- (9CI) Morphinan-6b,14-diol, 3,4-dimethoxy-17-methyl- (8CI) oxymetebanol Oxymethebanol 3,4-Dimethoxy-17-methylmorphinan-6β,14-diol 3,4-Dimethoxy-17-methylmorphinan-6β,14β-diol (6β)-3,4-DiMethoxy-17-MethylMorphinan-6,14-diol 6β,14-Dihydroxy-3,4-diMethoxy-N-MethylMorphinan Dihydro-14-hydroxy-4-O-Methyl-6β-thebainol Dihydro-14-hydroxy-6β-thebainol 4-Methyl Ether LCAHPIFLPICNRW-SVYNMNNPSA-N Morphinan-6,14-diol, 3,4-dimethoxy-17-methyl-, (6β)- 3176-03-2 Amines Aromatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals