ChemicalBook >> CAS DataBase List >>(9S)-9-Amino-9-deoxoerythromycin
(9S)-9-Amino-9-deoxoerythromycin
- CAS No.
- 26116-56-3
- Chemical Name:
- (9S)-9-Amino-9-deoxoerythromycin
- Synonyms
- LY 024410;Brn 4241492;BRL 42852ER;Erythromycylamine;Erythromycilamine;9-Epierythromycylamine;Epierythromycyl-A-amine;9-(S)-AMINOERYTHROMYCIN;(9S)-erythromycyclamine;(9S)-Erythromycylamine A
- CBNumber:
- CB41236921
- Molecular Formula:
- C37H70N2O12
- Molecular Weight:
- 734.96
- MDL Number:
- MFCD00872156
- MOL File:
- 26116-56-3.mol
- MSDS File:
- SDS
Last updated:2024-04-26 14:50:00
| Melting point | 123-127°C |
|---|---|
| Boiling point | 810.3±65.0 °C(Predicted) |
| Density | 1.19±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMF: 15 mg/ml; DMSO: 15 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml |
| form | A solid |
| pka | 13.41±0.70(Predicted) |
| EWG's Food Scores | 1 |
| FDA UNII | YX9KV1OMA4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H318-H410 | |||||||||
| Precautionary statements | P280-P305+P351+P338-P310-P273-P391-P501 | |||||||||
| Hazard Codes | Xi,N | |||||||||
| Risk Statements | 41-50/53 | |||||||||
| Safety Statements | 26-39-60-61 | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,120mg/kg (120mg/kg),European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 13, Pg. 83, 1978. | |||||||||
| NFPA 704 |
|
(9S)-9-Amino-9-deoxoerythromycin price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28098 | Erythromycylamine | 26116-56-3 | 1mg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 28098 | Erythromycylamine | 26116-56-3 | 10mg | $903 | 2024-03-01 | Buy |
| Cayman Chemical | 28098 | Erythromycylamine | 26116-56-3 | 5mg | $481 | 2024-03-01 | Buy |
| Usbiological | 257299 | Erythromycylamine | 26116-56-3 | 1mg | $531 | 2021-12-16 | Buy |
| TRC | E653400 | Erythromycylamine | 26116-56-3 | 10mg | $1070 | 2021-12-16 | Buy |
(9S)-9-Amino-9-deoxoerythromycin Chemical Properties,Uses,Production
Chemical Properties
(9S)-9-Amino-9-deoxoerythromycin is White Solid
Uses
(9S)-9-Amino-9-deoxoerythromycin is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. (9S)-9-Amino-9-deoxoerythromycin is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. This limitation was overcome by the synthesis of dirithromycin, a Schiff base pro-drug that dissociates in vivo to erythromycylamine.
Uses
Erythromycylamine is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. Erythromycylamine is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. This limitation was overcome by the synthesis of dirithromycin, a Schiff base pro-drug that dissociates in vivo to erythromycylamine.
Uses
(9S)-9-Amino-9-deoxoerythromycin is a metabolite of Dirithromycin; an antibiotic
Definition
ChEBI: A macrolide antibiotic that is erythromycin A in which the ketone group has been converted to the corresponding imine and then reduced to give the corresponding amino compound (the 9S diastereoisomer).
(9S)-9-Amino-9-deoxoerythromycin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 81)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
View Lastest Price from (9S)-9-Amino-9-deoxoerythromycin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-26 | (9S)-9-Amino-9-deoxoerythromycin
26116-56-3
|
US $1.00 / g | 1g | ≥98% | g/kg/Ton | Career Henan Chemical Co |
-
- (9S)-9-Amino-9-deoxoerythromycin
26116-56-3
- US $1.00 / g
- ≥98%
- Career Henan Chemical Co
26116-56-3((9S)-9-Amino-9-deoxoerythromycin)Related Search:
(9S)-9-Amino-9-deoxoerythromycin
(9S)-9-amino-9-deoxyerythromycin
9-Amino-9-deoxo-erythromycin, stereoisomer
9-Epierythromycylamine
Brn 4241492
Epierythromycyl-A-amine
Erythromycin, 9-amino-9-deoxo-, (9S)- (9ci)
Erythromycin, 9-amino-9-deoxo-, stereoisomer
(9S)-9-AMiNA-9-deoxoerythroMycin
9-(S)-AMINOERYTHROMYCIN
9-(S)-ERYTHROMYCYLAMINE:9-AMINO-9-DEOXO-ERYTHROMYCIN
(9S)-9-Deoxy-9-aminoerythromycin A
(9S)-Erythromycylamine A
BRL 42852ER
Erythromycylamine
LY 024410
(9s)-9-aMino-9-deoxoeryhtroMycin
9(S) ErythroMycylaMin A, BRL 42852ER, LY 024410
(9S)-erythromycyclamine
Dirithromycin EP impurity A
(9S)-9-Amino-9-deoxoerythromycin (9S)-9-Amino-9-deoxoerythromycin
Dirithromycin impurity A
Dirithromycin Impurity 1(Dirithromycin EP Impurity A)
Dirithromycin EP Impurity A/Erythromycylamine/(3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-10-amino-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimeth
Dirithromycin Impurit Ⅰ: (9S)-9-Amino-9-deoxoerythromycin
Erythromycilamine
Dirithromycin EP Impurity A (Erythromycylamine)
Erythromycin, 9-amino-9-deoxo-, (9S)-
Erythromycylamine (Dirithromycin EP Impurity A)
Erythromycylamine-13C-d3
(3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-10-Amino-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
Erythromycylamine-13C-d3 (Dirithromycin EP Impurity A-13C-d3)
erythromyclamine, (9R)-isomer
(9S)-9-Amino-9-deoxoerythromycin (Dirithromycin Impurity)
26116-56-3
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals
Various Metabolites and Impurities