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ChemicalBook >> CAS DataBase List >>(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one

(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one

(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one Structure
(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one structure
CAS No.
667-66-3
Chemical Name:
(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one
Synonyms
B-Cortolone;2-Cortolone;β-Cortolone;β-Cortolone D5;5β-pregnan-3α, 17, 20β, 21-tetrol-11-one;5β-PREGNAN-3α, 17, 20β, 21-TETROL-11-ONE;(20R)-3α,17α,20,21-Tetrahydroxy-5β-pregnan-11-one;Pregnan-11-one, 3,17,20,21-tetrahydroxy-, (3α,5β,20R)-;(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one
CBNumber:
CB41260847
Molecular Formula:
C21H34O5
Molecular Weight:
366.495
MDL Number:
MOL File:
667-66-3.mol
Last updated:2023-06-08 09:03:09
Request For Quotation

(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one Properties

Melting point 249-258oC
Boiling point 564.1±50.0 °C(Predicted)
Density 1.248±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly, Heated), Methanol (Slightly, Heated), Pyridine (Slightly)
pka 13.95±0.70(Predicted)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P321-P305+P351+P338-P332+P313-P362+P364-P337+P313
NFPA 704
0
2 0

(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C696285 β-Cortolone 667-66-3 50mg $595 2021-12-16 Buy
Medical Isotopes, Inc. 63783 β-Cortolone 667-66-3 10mg $490 2021-12-16 Buy
Product number Packaging Price Buy
C696285 50mg $595 Buy
63783 10mg $490 Buy

(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one Chemical Properties,Uses,Production

Uses

β-Cortolone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.

Definition

ChEBI: Beta-Cortolone is a 21-hydroxy steroid.

(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one Preparation Products And Raw materials

Raw materials

Preparation Products

(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one Suppliers

Global( 13)Suppliers
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Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7892 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632 sales@reading-chemicals.com China 15185 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Wuxi Helen Biotechnology Co., Ltd., 0510-85629785 18013409632 sales@reading-chemicals.com China 14092 58
Shanghai Hewu Biotechnology Co., LTD 021-57886085 17317861055 shhebio@126.com CHINA 7975 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Foshan Treasure Biotechnology Co., Ltd 0757-85921206 18520245316 2329783215@qq.com China 12664 58
Shanghai Saikerui Biotechnology Co. , Ltd. 021-58000709 15900491054 info@scrbio.com China 9267 58
SHANGHAI ZZBIO CO., LTD. 021-58979353 18019707223 tech@zzbioco.com China 12096 58
Supplier Advantage
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Shanghai EFE Biological Technology Co., Ltd. 58
Wuxi Helen Biotechnology Co., Ltd., 58
Shanghai Hewu Biotechnology Co., LTD 58
Energy Chemical 58
Foshan Treasure Biotechnology Co., Ltd 58
Shanghai Saikerui Biotechnology Co. , Ltd. 58
SHANGHAI ZZBIO CO., LTD. 58

667-66-3((3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one)Related Search:

5B-PREGNANE-3A-17A-20B-TRIOL*CRYSTALLINE 5BETA-PREGNAN-3ALPHA, 17ALPHA, 20BETA, 21-TETROL-11-ONE-3BETA-D-GLUCURONIDE-20 21-ACETONIDE (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one 2-HEPTANONE，5-(HYDROXYMETHYL) Menthone
5-BETA-PREGNAN-3-ALPHA, 20-BETA-DIOL

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(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one B-Cortolone (20R)-3α,17α,20,21-Tetrahydroxy-5β-pregnan-11-one 2-Cortolone 5β-pregnan-3α, 17, 20β, 21-tetrol-11-one β-Cortolone β-Cortolone D5 Pregnan-11-one, 3,17,20,21-tetrahydroxy-, (3α,5β,20R)- 5β-PREGNAN-3α, 17, 20β, 21-TETROL-11-ONE 667-66-3