chlorazine
- CAS No.
- 580-48-3
- Chemical Name:
- chlorazine
- Synonyms
- G25804;chlorazine;S-TRIAZINE,2-CHLORO-4,6-BIS(DIETHYLAMINO)-;2,4-Di-(N,N'-Diethylamino)-6-Chlorotriazine;2,4-DI-(N,N'-DIETHYLAMINO)-6-CHLOROTRIAZINE;2,4-bis(N,N-diethylamino)-6-chloro-1,3,5-triazine;[4-chloro-6-(diethylamino)-s-triazin-2-yl]-diethyl-amine;6-chloro-N2,N2,N4,N4-tetraethyl-1,3,5-triazine-2,4-diamine;1,3,5-Triazine-2,4-diamine, 6-chloro-N2,N2,N4,N4-tetraethyl-;6-chloro-2-N,2-N,4-N,4-N-tetraethyl-1,3,5-triazine-2,4-diamine
- CBNumber:
- CB4126737
- Molecular Formula:
- C11H20ClN5
- Molecular Weight:
- 257.76
- MDL Number:
- MFCD00080472
- MOL File:
- 580-48-3.mol
- MSDS File:
- SDS
| Melting point | 27°C |
|---|---|
| Boiling point | 404.64°C (rough estimate) |
| Density | 1.0956 |
| refractive index | 1.5320 (estimate) |
| pka | 3.18±0.10(Predicted) |
| Water Solubility | 10mg/L(21 ºC) |
| FDA UNII | T60AV22R32 |
| EPA Substance Registry System | Chlorazine (580-48-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
chlorazine Chemical Properties,Uses,Production
Description
Chlorazine is a drug that belongs to the class of phenothiazines. It is used in the treatment of nausea and vomiting, as well as for sedation before surgery or endoscopy, but it also has some undesirable side effects. Chlorazine can be detected by chromatographic analysis and is biocompatible with polymer matrices. The drug has been shown to inhibit the growth of cells (in-vitro) by binding to cell nuclei. The chlorazine molecule has been found to have significant upregulation on α7 nicotinic acetylcholine receptors and pharmacological agents such as receptor activity. This drug may also have a matrix effect on chemical inhibitors.
Chemical Properties
Solid. Soluble in hydrocarbons, alcohols, ketones; insoluble in water.
Uses
Herbicide.
Preparation
Chlorazine is formed through a reaction between cyanuric chloride and diethylamine.
Mode of action
Their chief mode of action appears to involve carbohydrate metabolism. The chlorinated s-triazines inhibit starch accumulation by blocking the production of sugars. Similar behavior has been shown for the methoxy & methylthio-s-triazines. It has been reported that the s-triazines affect the tricarboxylic acid cycle with activation of phospho-phenyl pyruvate-carboxylase causing the disappearance of sucrose & glyceric acid with the formation of aspartic & malic acids.
chlorazine Preparation Products And Raw materials
chlorazine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Jinan Tai Hang Seng Material Technology Co., LTD | 17852565707 | 157163860@qq.com | China | 14 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006608290; 18621169109 | market03@meryer.com | China | 40241 | 62 |
| Shaanxi Yikunte Pharmaceutical Technology Co., Ltd. | 18049260030 | 380381031@qq.com | China | 508 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
| Hefei Mokai Pharmaceutical Technology Co., Ltd | 18130062233 | 3362556465@qq.com | China | 8000 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 15221909166 | product02@bidepharm.com | China | 61720 | 58 |
| Bide Pharmatech Ltd. | 400-6005915 | sales@picasso-e.com | China | 39668 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 15229059051 | 1027@dideu.com | China | 9902 | 58 |