Anti-stromal interaction molecule 2
- CAS No.
- Chemical Name:
- Anti-stromal interaction molecule 2
- Synonyms
- Anti-stromal interaction molecule 2;Anti-STIM2 antibody produced in rabbit;Anti-STIM2 (ab2) antibody produced in rabbit;Anti-STIM2 (ab1) antibody produced in rabbit
- CBNumber:
- CB42102076
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-stromal interaction molecule 2 price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | S8572 | Anti-STIM2 antibody produced in rabbit ~1.0?mg/mL, affinity isolated antibody, buffered aqueous solution | 200μL | $528 | 2024-03-01 | Buy | |
Sigma-Aldrich | PRS4125 | Anti-STIM2 (ab2) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 100μg | $524 | 2024-03-01 | Buy | |
Sigma-Aldrich | PRS4123 | Anti-STIM2 (ab1) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 100μg | $524 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA057511 | Anti-STIM2 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $580 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA036933 | Anti-STIM2 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $580 | 2024-03-01 | Buy |
Anti-stromal interaction molecule 2 Chemical Properties,Uses,Production
Uses
Anti-STIM2 antibody produced in rabbit has been used in western blotting.
Uses
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
General Description
STIM (stromal interaction molecule) proteins are conserved single-pass transmembrane protein. The three STIM proteins, STIM1, STIM2 and D-Stim, are ubiquitously expressed proteins composed of a single SAM (sterile α-motif) domain and an unpaired EF hand within the highly conserved extracellular region and coiled-coil domains that are conserved in structure and position within the cytoplasmic region. Significant divergence between these proteins was found only at the extreme C-termini. STIM proteins are modified by phosphorylation and N-linked glycosylation.
Biochem/physiol Actions
STIM (stromal interaction molecule) required for the regulation of store-operated Ca2+ influx. Store-operated calcium entry is mediated by Ca2+ release-activated Ca2+ (CRAC) channels, following Ca2+ depletion from the endoplasmic reticulum (ER) stores. This process is crucial for gene transcription, proliferation and cytokine release. STIM2 is an inhibitor of STIM1-mediated store-operated Ca2+ entry. STIM2 co-localizes with STIM1 in punctae upon store depletion, and coprecipitates with STIM1 from cell lysates, suggesting that they may play a coordinated role in controlling Ca2+ entry.
Anti-stromal interaction molecule 2 Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-stromal interaction molecule 2 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |