17-phenyl trinor Prostaglandin F2α-d4
- CAS No.
- 58976-50-4
- Chemical Name:
- 17-phenyl trinor Prostaglandin F2α-d4
- Synonyms
- Bimatoprost Acid-d4;Bimatoprost, free acid-d4;Bimatoprost Impurity 5-d4;YFHHIZGZVLHBQZ-QOHQNJFUSA-N;17-phenyl trinor Prostaglandin F2α-d4;17-phenyl trinor Prostaglandin F2α-d4
- CBNumber:
- CB42589954
- Molecular Formula:
- C23H32O5
- Molecular Weight:
- 388.5
- MDL Number:
- MOL File:
- 58976-50-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319-H336 | |||||||||
| Precautionary statements | P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
| NFPA 704 |
|
17-phenyl trinor Prostaglandin F2α-d4 price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 316810 | 17-phenyl trinor Prostaglandin F2α-d4 ≥99% deuterated forms (d1-d4) | 58976-50-4 | 25μg | $72 | 2024-03-01 | Buy |
| Cayman Chemical | 316810 | 17-phenyl trinor Prostaglandin F2α-d4 ≥99% deuterated forms (d1-d4) | 58976-50-4 | 50μg | $135 | 2024-03-01 | Buy |
| Cayman Chemical | 316810 | 17-phenyl trinor Prostaglandin F2α-d4 ≥99% deuterated forms (d1-d4) | 58976-50-4 | 100μg | $255 | 2024-03-01 | Buy |
| Cayman Chemical | 316810 | 17-phenyl trinor Prostaglandin F2α-d4 ≥99% deuterated forms (d1-d4) | 58976-50-4 | 1mg | $1829 | 2024-03-01 | Buy |
| aablocks | AA00EBIH | 17-phenyltrinorProstaglandinF2α-d4 ≥99%deuteratedforms(d1- |
58976-50-4 | 1mg | $1935 | 2021-12-16 | Buy |
17-phenyl trinor Prostaglandin F2α-d4 Chemical Properties,Uses,Production
Definition
ChEBI: 17-phenyl trinor Prostaglandin F2alpha-d4 is a prostanoid.
Biological Activity
17-phenyl trinor Prostaglandin F2α-d4 (17-phenyl trinor PGF2α-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 17-phenyl trinor PGF2α by GC- or LC-mass spectrometry. 17-phenyl trinor PGF2α is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. It binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α.1 At the rat recombinant FP receptor expressed in CHO cells 17-phenyl trinor PGF2α inhibits PGF2α binding with a Ki of 1.1 nM.2 The isopropyl ester of 17-phenyl trinor PGF2α-d4 is slightly better than PGF2α isopropyl ester in reducing the intraocular pressure in the cat eye without any irritation.3
References
1.Balapure, A.K., Rexroad, C.E., Jr., Kawada, K., et al.Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2α receptorBiochem. Pharmacol.38(14)2375-2381(1989) 2.Lake, S., Gullberg, H., Wahlqvist, J., et al.Cloning of the rat and human prostaglandin F2α receptors and the expression of the rat prostaglandin F2α receptorFEBS Letters355317-325(1994) 3.Stjernschantz, J., and Resul, B.Phenyl substituted prostaglandin analogs for glaucoma treatmentDrugs of the Future17691-704(1992)
17-phenyl trinor Prostaglandin F2α-d4 Preparation Products And Raw materials
Raw materials
Preparation Products
17-phenyl trinor Prostaglandin F2α-d4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Hangzhou Synstar pharmaceutical Technology CO.,Ltd | 0571-85361029 | synstar518@163.com | China | 1991 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd | 18502726233 | 3641133981@qq.com | China | 9382 | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | market@aladdin-e.com | China | 48467 | 58 |