25-hydroxy Cholesterol-d6
- CAS No.
- 88247-69-2
- Chemical Name:
- 25-hydroxy Cholesterol-d6
- Synonyms
- 25-hydroxy Cholesterol-d6;cholest-5-ene-3,25-diol-d6;cholest-5-ene-3β,25-diol-d6;CHOLEST-5-ENE-3,25-DIOL-D6;25-HYDROXYCHOLESTEROL-D6;(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-7,7,7-trideuterio-6-hydroxy-6-(trideuteriomethyl)heptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
- CBNumber:
- CB42589994
- Molecular Formula:
- C27H40D6O2
- Molecular Weight:
- 408.689910668
- MDL Number:
- MOL File:
- 88247-69-2.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H301+H311+H331-H370 | |||||||||
| Precautionary statements | P210-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311 | |||||||||
| NFPA 704 |
|
25-hydroxy Cholesterol-d6 price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 11099 | 25-hydroxy Cholesterol-d6 ≥99% deuterated forms (d1-d6) | 88247-69-2 | 500μg | $63 | 2024-03-01 | Buy |
| Cayman Chemical | 11099 | 25-hydroxy Cholesterol-d6 ≥99% deuterated forms (d1-d6) | 88247-69-2 | 1mg | $117 | 2024-03-01 | Buy |
| Cayman Chemical | 11099 | 25-hydroxy Cholesterol-d6 ≥99% deuterated forms (d1-d6) | 88247-69-2 | 5mg | $486 | 2024-03-01 | Buy |
| Usbiological | 160140 | 25-Hydroxy Cholesterol-d6 | 88247-69-2 | 1mg | $460 | 2021-12-16 | Buy |
| TRC | H918032 | 25-HydroxyCholesterol-d6 | 88247-69-2 | 10mg | $1190 | 2021-12-16 | Buy |
25-hydroxy Cholesterol-d6 Chemical Properties,Uses,Production
Uses
25-Hydroxy Cholesterol-d6, is the labeled analogue of 25-Hydroxy Cholesterol (H918030), which is an oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It also induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.
General Description
25-hydroxycholesterol (25HC) is synthesized from cholesterol in the presence of oxygen and enzyme cholesterol 25-hydroxylase and the conversion is dependent on nicotinamide adenine dinucleotide phosphate (NADPH) during toll-like receptor activation. 25HC is catabolized to 7α-hydroxylated sterol. 25-hydroxycholesterol-d6 is the deuterated form of 25-hydroxycholesterol.
Biochem/physiol Actions
25-hydroxycholesterol inhibits cholesterol biosynthesis by downregulating the function of 3-hydroxy-3-methylglutaryl-CoA reductase. It is found to be implicated in atherosclerosis. 25-hydroxycholesterol levels are known to be increased in hypercholesterolemic condition.
25-hydroxy Cholesterol-d6 Preparation Products And Raw materials
Raw materials
Preparation Products
25-hydroxy Cholesterol-d6 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shandong Xiya Chemical Co., Ltd | 4009903999 13355009207 | 3007715519@qq.com | China | 18738 | 57 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | market@aladdin-e.com | China | 25009 | 65 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9685 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17698 | 55 |
| Chemaphor Chemical Services. | (613) 656-7272 | l.elliott@chemaphor.com | Canada | 22 | 58 |
| Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 | cdhxsj@163.com | China | 14623 | 60 |
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 17361806303 | 3004208264@qq.com | China | 3022 | 58 |