ChemicalBook >> CAS DataBase List >>LAS101057
LAS101057
- CAS No.
- 925676-48-8
- Chemical Name:
- LAS101057
- Synonyms
- LAS101057;LAS-101057,LAS101057;N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide;Cyclopropanecarboxamide, N-[5-(3-fluoro-4-pyridinyl)-6-(3-pyridinyl)-2-pyrazinyl]-;N-(5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)pyrazin-2-yl)cyclopropanecarboxamide(WXFC0500)
- CBNumber:
- CB42628024
- Molecular Formula:
- C18H14FN5O
- Molecular Weight:
- 335.34
- MDL Number:
- MOL File:
- 925676-48-8.mol
- MSDS File:
- SDS
Last updated:2024-07-02 08:55:08
| Boiling point | 509.2±50.0 °C(Predicted) |
|---|---|
| Density | 1.400±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO:125.0(Max Conc. mg/mL);372.75(Max Conc. mM) |
| form | A solid |
| pka | 11.70±0.20(Predicted) |
| color | White to off-white |
| FDA UNII | 3EBU6WKP85 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| NFPA 704 |
|
LAS101057 price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28435 | LAS101057 | 925676-48-8 | 5mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 28435 | LAS101057 | 925676-48-8 | 10mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 28435 | LAS101057 | 925676-48-8 | 25mg | $254 | 2024-03-01 | Buy |
| Cayman Chemical | 28435 | LAS101057 | 925676-48-8 | 50mg | $477 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | API0013975 | LAS-101057 95.00% | 925676-48-8 | 5MG | $495 | 2021-12-16 | Buy |
LAS101057 Chemical Properties,Uses,Production
Uses
LAS 101057 is a potent, selective, and orally efficacious A2B receptor antagonist, was identified as a clinical development candidate. It inhibits agonist-induced IL-6 production in human fibroblasts and is active in an ovalbumin (OVA)-sensitized mouse model after oral administration, reducing airway hyperresponsiveness to methacholine, Th2 cytokine production and OVA-specific IgE levels.
LAS101057 Preparation Products And Raw materials
Raw materials
Preparation Products
LAS101057 Suppliers
Global( 20)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10297 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| Shanghai Balmxy Pharmaceutical Co., Ltd | 021-24206007 13764915196 | sales@balmxy.com | China | 6765 | 55 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 18112977050 | cb6@aikonchem.com | China | 16687 | 50 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
| Shanghai ZiHao Pharmaceutical Co., Ltd. | 021-13482410-12 13482410112 | 362383684@qq.com | China | 731 | 58 |
| Cool Pharm, Ltd | 18019463053 | sales@coolpharm.com | China | 13017 | 58 |
LAS101057
N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide
N-(5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)pyrazin-2-yl)cyclopropanecarboxamide(WXFC0500)
Cyclopropanecarboxamide, N-[5-(3-fluoro-4-pyridinyl)-6-(3-pyridinyl)-2-pyrazinyl]-
LAS-101057,LAS101057
925676-48-8