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ChemicalBook >> CAS DataBase List >> LAS101057

LAS101057

$32 - $525
Product name: LAS101057
CAS: 925676-48-8
MF: C18H14FN5O
MW: 335.34
EINECS:
MDL Number:
Synonyms:LAS101057;N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide;N-(5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)pyrazin-2-yl)cyclopropanecarboxamide(WXFC0500);Cyclopropanecarboxamide, N-[5-(3-fluoro-4-pyridinyl)-6-(3-pyridinyl)-2-pyrazinyl]-;LAS-101057,LAS101057;LAS101057, 10 mM in DMSO

Price25 Properties Safety Information Description

25 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
AK Scientific
American Custom Chemicals Corporation
Arctom
Cayman Chemical
Chemenu
ChemScene

Package

10mM*1mLinDMSO(Solid+Solvent)
5mg
10mM*1mLinDMSO(Solution)
10mg
25mg
50mg
100MG

Manufactureraablocks
Product numberAA01DFE5
Product descriptionN-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide 98%
Packaging5mg
Price$58
Updated2026-05-29
Buy

Manufactureraablocks
Product numberAA01DFE5
Product descriptionN-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide 98%
Packaging10mg
Price$86
Updated2026-05-29
Buy

Manufactureraablocks
Product numberAA01DFE5
Product descriptionN-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide 98%
Packaging50mg
Price$273
Updated2026-05-29
Buy

Manufactureraablocks
Product numberAA01DFE5
Product descriptionN-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide 98%
Packaging25mg
Price$161
Updated2026-05-29
Buy

ManufacturerACHEMBLOCK
Product numberAD251410
Product descriptionLAS101057 98%
Packaging100MG
Price$330
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberAD251410
Product descriptionLAS101057 98%
Packaging25MG
Price$145
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number2229CW
Product descriptionCID16071896
Packaging10mg
Price$218
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0013975
Product descriptionLAS-101057 95.00%
Packaging5MG
Price$495
Updated2021-12-16
Buy

ManufacturerArctom
Product numberHY-14390
Product descriptionLAS101057 99.92%
Packaging50mg
Price$146
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-14390
Product descriptionLAS101057 99.92%
Packaging25mg
Price$97
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-14390
Product descriptionLAS101057 99.92%
Packaging10mg
Price$48
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-14390
Product descriptionLAS101057 99.92%
Packaging5mg
Price$32
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-14390
Product descriptionLAS101057 99.92%
Packaging10mM*1mLinDMSO(Solid+Solvent)
Price$33
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-14390
Product descriptionLAS101057 99.92%
Packaging10mM*1mLinDMSO(Solution)
Price$35
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-14390
Product descriptionLAS101057 99.92%
Packaging100mg
Price$219
Updated2026-05-26
Buy

ManufacturerCayman Chemical
Product number28435
Product descriptionLAS101057 ≥95%
Packaging10mg
Price$120
Updated2026-04-30
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA01DFE5	N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide 98%	5mg	$58	2026-05-29	Buy
aablocks	AA01DFE5	N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide 98%	10mg	$86	2026-05-29	Buy
aablocks	AA01DFE5	N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide 98%	50mg	$273	2026-05-29	Buy
aablocks	AA01DFE5	N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide 98%	25mg	$161	2026-05-29	Buy
ACHEMBLOCK	AD251410	LAS101057 98%	100MG	$330	2026-05-27	Buy
ACHEMBLOCK	AD251410	LAS101057 98%	25MG	$145	2026-05-27	Buy
AK Scientific	2229CW	CID16071896	10mg	$218	2021-12-16	Buy
American Custom Chemicals Corporation	API0013975	LAS-101057 95.00%	5MG	$495	2021-12-16	Buy
Arctom	HY-14390	LAS101057 99.92%	50mg	$146	2026-05-26	Buy
Arctom	HY-14390	LAS101057 99.92%	25mg	$97	2026-05-26	Buy
Arctom	HY-14390	LAS101057 99.92%	10mg	$48	2026-05-26	Buy
Arctom	HY-14390	LAS101057 99.92%	5mg	$32	2026-05-26	Buy
Arctom	HY-14390	LAS101057 99.92%	10mM*1mLinDMSO(Solid+Solvent)	$33	2026-05-26	Buy
Arctom	HY-14390	LAS101057 99.92%	10mM*1mLinDMSO(Solution)	$35	2026-05-26	Buy
Arctom	HY-14390	LAS101057 99.92%	100mg	$219	2026-05-26	Buy
Cayman Chemical	28435	LAS101057 ≥95%	10mg	$120	2026-04-30	Buy

Next Last

Properties

Boiling point :509.2±50.0 °C(Predicted)
Density :1.400±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO:125.0(Max Conc. mg/mL);372.75(Max Conc. mM)
form :A solid
pka :11.70±0.20(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

LAS 101057 is a potent, selective, and orally efficacious A2B receptor antagonist, was identified as a clinical development candidate. It inhibits agonist-induced IL-6 production in human fibroblasts and is active in an ovalbumin (OVA)-sensitized mouse model after oral administration, reducing airway hyperresponsiveness to methacholine, Th2 cytokine production and OVA-specific IgE levels.

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Suppliers and manufacturers

BOC Sciences MedChemexpress LLC Shanghai Balmxy Pharmaceutical Co., Ltd Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. Shanghai ZiHao Pharmaceutical Co., Ltd. Lanzhou Kangyuxin Biotechnology Co., Ltd. TargetMol Chemicals Inc. Amel Pharmatech Corporation

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LAS101057

Properties

Safety Information

Description

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