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MASTOPARAN

CAS No.
72093-21-1
Chemical Name:
MASTOPARAN
Synonyms
MASTOPARAN;NSC 351907;Mastoparan-1;INLKALAALAKKIL;INLKALAALAKKIL-NH2;Mastoparan(acetate);MASTOPARAN USP/EP/BP;MASTOPARAN 4ACOH 6H2O;MASTOPARAN VESPULA LEWISII;Mastoparan from Vespula lewisii
CBNumber:
CB4292335
Molecular Formula:
C70H131N19O15
Molecular Weight:
1478.91
MDL Number:
MFCD00076865
MOL File:
72093-21-1.mol
MSDS File:
SDS
Last updated:2024-03-27 11:49:37

MASTOPARAN Properties

Boiling point 1676.8±65.0 °C(Predicted)
Density 1.150±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility H2O: 1 mg/mL, clear, colorless
form White solid
pka 13.43±0.46(Predicted)
color white
BRN 5491949
Sequence H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H334-H317
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501
Safety Statements  22-24/25
WGK Germany  3
10

MASTOPARAN price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M5280 Mastoparan, Vespula lewisii ≥97% (HPLC), powder 72093-21-1 1mg $98.4 2024-03-01 Buy
Sigma-Aldrich 444898 Mastoparan A cell-permeable synthetic peptide with sequence identical to 72093-21-1 1mg $230 2024-03-01 Buy
Cayman Chemical 20240 Mastoparan ≥95% 72093-21-1 500μg $55 2021-12-16 Buy
Cayman Chemical 20240 Mastoparan ≥95% 72093-21-1 1mg $88 2021-12-16 Buy
Sigma-Aldrich M5280 Mastoparan, Vespula lewisii ≥97% (HPLC), powder 72093-21-1 5mg $660 2024-03-01 Buy
Product number Packaging Price Buy
M5280 1mg $98.4 Buy
444898 1mg $230 Buy
20240 500μg $55 Buy
20240 1mg $88 Buy
M5280 5mg $660 Buy

MASTOPARAN Chemical Properties,Uses,Production

Uses

Mastoparan has been used as a calmodulin antagonist.

Definition

ChEBI: A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, leucyl, lysyl, alanyl, leucyl, alanyl, alanyl, leucyl, alanyl, lysyl, lysyl, isoleucyl, and leucinamide residues coupled in sequence. It is the majo active component of the venom of the vespid wasp, Vespula lewisii and causes degranulation of mast cells.

General Description

Mastoparan is a cationic, amphiphilic, tetradecapeptide amide. It is composed of the restricted amino acid and the repeated sequence. This protein is a nonspecific secretagogue isolated from venom of wasp.

Biochem/physiol Actions

Mastoparan effectively stimulates exocytosis from diverse mammalian cells. The encoded protein facilitates the secretion of histamine from mast cells, serotonin from platelets, catecholamines from chromaffin cells and prolactin from the anterior pituitary. In addition, it is also involved in activation of Phospholipase A2 and phosphoinositides (Pl) break down. Mastoparan functions as an inhibitor for calmodulin-stimulated phosphodiesterase. Mastoparan helps in mitochondrial permeability transition by enhancing an apparent bimodal mechanism of action.

MASTOPARAN Preparation Products And Raw materials

Raw materials

Preparation Products

MASTOPARAN Suppliers

Global( 125)Suppliers
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ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU-NH2 ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU-NH2 4ACOH 6H2O Mastcelldegranulatingpeptide(Vespulalewisii) Mastoparan from Vespula lewisii MASTOPARAN TRIFLUOROACETATE SALT >99% PE PTIDE FROM WASP VEN L-Ile-L-Asn-L-Leu-L-Lys-L-Ala-L-Leu-L-Ala-L-Ala-L-Leu-L-Ala-L-Lys-L-Lys-L-Ile-L-Leu-NH2 MASTOPARAN MASTOPARAN 4ACOH 6H2O MASTOPARAN VESPULA LEWISII INLKALAALAKKIL INLKALAALAKKIL-NH2 H-ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU-NH2 MASTOPARAN USP/EP/BP Mastoparan-1 NSC 351907 Mastoparan(acetate) 72093-21-1 C70H131N19O15 C70H129N19O15 Other Peptides Peptides BioChemical Biochemicals and Reagents Amino Acids and Peptides Peptide Phospholipase ActivatorsCell Signaling and Neuroscience Phospholipid Metabolism Lipids in Cell Signaling Toxins and Venoms Wasp G-Protein