MHY 908
- CAS No.
- 1393371-39-5
- Chemical Name:
- MHY 908
- Synonyms
- MHY 908;MHY908,MHY-908;Propanoic acid, 2-[4-(5-chloro-2-benzothiazolyl)phenoxy]-2-methyl-
- CBNumber:
- CB43146329
- Molecular Formula:
- C17H14ClNO3S
- Molecular Weight:
- 347.82
- MDL Number:
- MOL File:
- 1393371-39-5.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| NFPA 704 |
|
MHY 908 price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 18293 | MHY908 ≥98% | 1393371-39-5 | 500μg | $48 | 2024-03-01 | Buy |
| Cayman Chemical | 18293 | MHY908 ≥98% | 1393371-39-5 | 1mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 18293 | MHY908 ≥98% | 1393371-39-5 | 5mg | $301 | 2024-03-01 | Buy |
| Cayman Chemical | 18293 | MHY908 ≥98% | 1393371-39-5 | 10mg | $508 | 2024-03-01 | Buy |
| TRC | M340985 | MHY908 | 1393371-39-5 | 25mg | $905 | 2021-12-16 | Buy |
MHY 908 Chemical Properties,Uses,Production
Description
MHY908 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ that increases transcriptional activity of PPARα and PPARγ in a luciferase reporter assay in AC2F rat liver cells when used at a concentration of 5 μM. In vivo, MHY908 (3 mg/kg per day) reduces serum glucose, triglyceride, and insulin levels and improves hepatic steatosis by reducing hepatic triglyceride levels and lipid droplet accumulation in db/db mice and 20-month-old rats. It reduces peroxynitrite and COX-2 levels, reactive oxygen species (ROS) production, and Akt phosphorylation in isolated kidney from 20-month-old rats when administered at a dose of 3 mg/kg. MHY908 inhibits mushroom tyrosinase (IC50 = 8.19 μM). It also inhibits increases in melanin content in α-melanocyte stimulating hormone-induced B16/F10 murine melanoma cells when used at a concentration of 10 μM.
Uses
MHY908 is a dual agonist of PPARα and PPARγ.
MHY 908 Preparation Products And Raw materials
Raw materials
Preparation Products
MHY 908 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 | sales@tybiochem.com | China | 5020 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9146 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |