2,5-Dimethoxyphenethylamine hydrochloride
- CAS No.
- 3166-74-3
- Chemical Name:
- 2,5-Dimethoxyphenethylamine hydrochloride
- Synonyms
- 2C-H (hydrochloride);Dopamine Impurity 24 HCl;2,5-DIMETHOXYPHENETHYLAMINE HCL;2,5-Dimethoxyphenylethylamine HCl;Dopamine hydrochloride impurity 35;2-(2,5-DiMethoxy-phenyl)-ethylaMine HCl;2,5-dimethoxy-phenethylaminhydrochloride;2C-H (hydrochloride) (exempt preparation);2,5-DIMETHOXY PHENETHYLAMINE HYDROCHLORIDE;2,5-DIMETHOXY PHENETHYLAMINE HYDORCHLORIDE
- CBNumber:
- CB4317618
- Molecular Formula:
- C10H16ClNO2
- Molecular Weight:
- 217.69
- MDL Number:
- MFCD01708299
- MOL File:
- 3166-74-3.mol
- MSDS File:
- SDS
| Melting point | 139 °C |
|---|---|
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 10 mg/ml |
| form | A crystalline solid |
| InChI | InChI=1S/C10H15NO2.ClH/c1-12-9-3-4-10(13-2)8(7-9)5-6-11;/h3-4,7H,5-6,11H2,1-2H3;1H |
| InChIKey | PJMQBIMLDBAWRK-UHFFFAOYSA-N |
| SMILES | C1(CCN)=C(OC)C=CC(OC)=C1.[H+].[Cl-] |
| CAS DataBase Reference | 3166-74-3(CAS DataBase Reference) |
| FDA UNII | P2Y262S9PP |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| NFPA 704 |
|
2,5-Dimethoxyphenethylamine hydrochloride price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 11889 | 2C-H (hydrochloride) ≥98% | 3166-74-3 | 5mg | $62 | 2026-04-30 | Buy |
| Cayman Chemical | 15715 | 2C-H (hydrochloride) (exempt preparation) ≥98% | 3166-74-3 | 1mg | $69 | 2026-04-30 | Buy |
| Cayman Chemical | 11889 | 2C-H (hydrochloride) ≥98% | 3166-74-3 | 10mg | $94 | 2026-04-30 | Buy |
| Cayman Chemical | 11889 | 2C-H (hydrochloride) ≥98% | 3166-74-3 | 50mg | $355 | 2026-04-30 | Buy |
| TRC | TRC-D460841-5MG | 2,5-Dimethoxyphenethylamine Hydrochloride | 3166-74-3 | 5mg | $211 | 2026-06-03 | Buy |
2,5-Dimethoxyphenethylamine hydrochloride Chemical Properties, Uses, Production
Description
A series of 2,5-
Uses
A series of 2,5-phenethylamines, collectively referred to as 2Cs, have psychoactive effects. The most effective 2C compounds are 2,5-dimethoxy-4-substituted phenethylamines; many are scheduled as ille gal substances. This product is intended for research and forensic applications.
Synthesis
2,5-dimethoxybenzaldehyde 3.32 g (0.02 mol), ammonium acetate 0.5 g and 4 mL of nitromethane were put into a reaction flask together, heated to 85 C with stirring, kept warm for 30 min, poured the reaction product into cold water while it was still hot, cooled, and yellow crystals were precipitated, filtered, and washed with 70% of ethanol to obtain 2,5-dimethoxy--nitroaniline 3.7 g (Yield 90%). 2,5-dimethoxy--nitrostyrene 4.18g added to 250mL three-necked flask, add 95% ethanol 20mL, stirring, heated to 40 , add concentrated hydrochloric acid 35mL, water 40mL; at 65 in batches to add 25g of zinc powder, adding a small amount of zinc powder after adding a small amount of metal mercury, keep the temperature between 65 ~ 70 ; add zinc powder than, reduce the temperature to 50 to join the Hydrochloric acid 10mL, maintain 50 ~ 55 3h; cooling, add sodium carbonate pH8 ~ 9, extracted with n-butanol, extract distillation under reduced pressure to remove n-butanol, the reaction into a dark brown slurry, weighing 6.5g. into the salt: to the slurry reactant to add methanol hydrochloric acid solution, evaporate most of the methanol, cooling precipitation, get light brown crystals of 2,5-dimethoxy--nitrophenethylene, 2.52g (yield 60%).
2,5-Dimethoxyphenethylamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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