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4-HYDROXYESTRONE

CAS No.
3131-23-5
Chemical Name:
4-HYDROXYESTRONE
Synonyms
4-OH-E1;4-HYDROXYESTRONE;Estrone Impurity 8;Estrone 4-Hydroxy Impurity;1,3,5(10)-ESTRATRIEN-3,4-DIOL-17-ONE;1,3,5[10]-ESTRATRIENE-3,4-DIOL-17-ONE;5(10)-trien-17-one,3,4-dihydroxy-estra-3;3,4-dihydroxyestra-1,3,5(10)-trien-17-one;3,4-DIHYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE;3,4-Dihydroxyestra-1(10),2,4-triene-17-one
CBNumber:
CB4353324
Molecular Formula:
C18H22O3
Molecular Weight:
286.37
MDL Number:
MFCD00079358
MOL File:
3131-23-5.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:18

4-HYDROXYESTRONE Properties

Melting point 260-263°C
Boiling point 468.2±45.0 °C(Predicted)
Density 1.241±0.06 g/cm3(Predicted)
Flash point 93 °C
storage temp. −20°C
solubility DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form Solid
pka 10.06±0.40(Predicted)
color Pale Yellow to Light Brown
FDA UNII 3MN57C55S2

SAFETY

Risk and Safety Statements

WGK Germany  3
RTECS  KG7749500

4-HYDROXYESTRONE price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H6012 4-Hydroxyestrone ≥90% (HPLC) 3131-23-5 5mg $242 2024-03-01 Buy
Sigma-Aldrich H6012 4-Hydroxyestrone ≥90% (HPLC) 3131-23-5 25mg $956 2024-03-01 Buy
TRC H941950 4-HydroxyEstrone 3131-23-5 5mg $130 2021-12-16 Buy
TRC H941950 4-HydroxyEstrone 3131-23-5 50mg $870 2021-12-16 Buy
Usbiological 279091 4-Hydroxy estrone 3131-23-5 1mg $425 2021-12-16 Buy
Product number Packaging Price Buy
H6012 5mg $242 Buy
H6012 25mg $956 Buy
H941950 5mg $130 Buy
H941950 50mg $870 Buy
279091 1mg $425 Buy

4-HYDROXYESTRONE Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Solid

Uses

A metabolite of Estradiol.

Definition

ChEBI: A 4-hydroxy steroid that is estrone substituted by a hydroxy group at position 4.

Hazard

A reproductive hazard.

Biochem/physiol Actions

4-Hydroxyestrone is an endogenous estrogen metabolite, which exhibits a strong neuroprotective effect against oxidative damage. It also provides effective protection against kanic acid-induced hippocampal oxidative damage in rats when compared to 17β-estradiol. 4-Hydroxyestrone regulates the angiogenic process during corpus luteum formation. It might be involved in an increased risk of cancer. 4-Hydroxyestrone is found in the early and mid-luteal phases.

4-HYDROXYESTRONE Preparation Products And Raw materials

Raw materials

Preparation Products

4-HYDROXYESTRONE Suppliers

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49999 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33349 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9685 58
ChemStrong Scientific Co.,Ltd 0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shandong JunRui Pharmaceutical Co., Ltd. 0539-5636807 15318528770 ffeng813@qq.com China 247 58
1,3,5[10]-ESTRATRIENE-3,4-DIOL-17-ONE 1,3,5(10)-ESTRATRIEN-3,4-DIOL-17-ONE 3,4-DIHYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE 4-HYDROXYESTRONE 3,4-dihydroxyestra-1,3,5(10)-trien-17-one 5(10)-trien-17-one,3,4-dihydroxy-estra-3 (9S,14S)-3,4-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 3,4-Dihydroxy-1(10),2,4-estratriene-17-one 3,4-Dihydroxyestra-1(10),2,4-triene-17-one 4-OH-E1 Estrone 4-Hydroxy Impurity Estra-1,3,5(10)-trien-17-one, 3,4-dihydroxy- Estrone Impurity 8 (8R,9S,13S,14S)-3,4-Dihydroxy-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one 3131-23-5 Various Metabolites and Impurities Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Steroids