CL 316243
- CAS No.
- 138908-40-4
- Chemical Name:
- CL 316243
- Synonyms
- CL 316243;CL-316243 sodium;CL 316,243 hydrate;COLLAGEN FROM HUMAN LUNG;CL 316243 disodium (CL316243 disodium);inhibit,Adrenergic Receptor,CL 316243,Inhibitor,Beta Receptor,CL-316243,CL316243;Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate;Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate
- CBNumber:
- CB4503291
- Molecular Formula:
- C20H18ClNO7.2Na
- Molecular Weight:
- 465.795
- MDL Number:
- MFCD00907153
- MOL File:
- 138908-40-4.mol
- MSDS File:
- SDS
storage temp. | room temp |
---|---|
solubility | H2O: >10 mg/mL |
form | solid |
color | white |
Water Solubility | Soluble to 100 mM in water |
FDA UNII | CF9MRO9QWW |
CL 316243 price More Price(18)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C5976 | CL 316,243 hydrate ≥98% (HPLC), powder | 138908-40-4 | 5mg | $267 | 2024-03-01 | Buy |
Sigma-Aldrich | C5976 | CL 316,243 hydrate ≥98% (HPLC), powder | 138908-40-4 | 25mg | $1080 | 2024-03-01 | Buy |
Cayman Chemical | 17499 | CL 316,243 ≥98% | 138908-40-4 | 500μg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 17499 | CL 316,243 ≥98% | 138908-40-4 | 1mg | $55 | 2024-03-01 | Buy |
Cayman Chemical | 17499 | CL 316,243 ≥98% | 138908-40-4 | 5mg | $139 | 2024-03-01 | Buy |
CL 316243 Chemical Properties,Uses,Production
Uses
CL 316243 Disodium Salt is a potent and highly selective β3-adrenoceptor agonist.
Uses
CL 316,243 hydrate has been used:
- as a β-agonists to inject mice and study its effect on the expression of mammalian major facilitator superfamily domain-containing protein (Mfsd2a)
- as an adrenergic agonist to stimulate adrenergic response in order to study the metabolic activity of brown, beige and white adipose tissues in mice
- as a β3-adrenergic agonist to inject mice for in vivo lipolytic challenge
Hazard
A poison.
Biochem/physiol Actions
β Adrenoceptor is expressed in a number of tissues such as heart, adipose tissue, colon and other tissues. It is associated with many different biological functions. β Adrenoceptor fills in as an objective for treating type 2 diabetes, heart failure, cachexia, obesity, metabolic disorder, issues related with bladder, colon and malignant tumor growth. Depression and anxiety can also be treated via β adrenoceptor. CL 316,243 is known to have antidiabetic action via β adrenoceptor. It is a potent stimulator of lipolysis. It also activates β3- adrenoceptors on neurons in hypothalamic areas that are important in the central regulation of appetite.
storage
Store at -20°C
CL 316243 Preparation Products And Raw materials
Raw materials
Preparation Products
CL 316243 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Kindchem(Nanjing)Co.,Ltd | +86-025-025-85281586 +8618651653755 | sales@kindchem.cn | China | 1227 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 18521732826; | market@aladdin-e.com | China | 25015 | 65 |
ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3420 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9440 | 58 |