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MJ 33

MJ 33 structure

CAS No.: 199106-13-3

Chemical Name:: MJ 33

Synonyms: MJ33-OH;Phosphoric acid, mono[1-[(hexadecyloxy)methyl]-2-(2,2,2-trifluoroethoxy)ethyl] mono(hydroxymethyl) ester

CBNumber:: CB4503837

Molecular Formula:: C22H44F3O7P

Molecular Weight:: 508.55

MDL Number:: MFCD03787978

MOL File:: 199106-13-3.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

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MJ 33 Properties

storage temp.	2-8°C
solubility	H2O: ≥5mg/mL (warmed at 60 °C)
form	solid
color	white to beige

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3

MJ 33 price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M3315	MJ33 lithium salt powder, ≥90% (NMR)	199106-13-3	5mg	$91.6	2024-03-01	Buy
TRC	M424303	MJ33	199106-13-3	100mg	$800	2021-12-16	Buy

Product number	Packaging	Price	Buy
M3315	5mg	$91.6	Buy
M424303	100mg	$800	Buy

MJ 33 Chemical Properties,Uses,Production

Uses

MJ33 lithium salt has been used as a peroxiredoxin VI (Prdx6) inhibitor:

to study its specific Prdx6 peroxidase activity in vitro and in breast cancer cell line (MCF-7) cell lysates
to study its effects on a mouse model of acute lung injury associated with exposure to hyperoxia
to study its potential use as a therapeutic agent

Biochem/physiol Actions

MJ33 acts as a non-toxic and potent inhibitor of agonist-induced activation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase type 2 (NOX2). It also prevents lung injuries associated with lung inflammation in mice. MJ33 is a fluorinated lipid analog, which blocks the enzyme by mimicking the transition state of the substrate.

MJ 33 Preparation Products And Raw materials

Raw materials

Preparation Products

MJ 33 Suppliers

Global( 10)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9414	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840	psaitong@jm-bio.com	China	29778	58
RD International Technology Co., Limited	18024082417	sales@ubiochem.com	China	9146	58

Supplier	Advantage
Aladdin Scientific	58
Sigma-Aldrich	80
DC Chemicals	58
Energy Chemical	58
Beijing Jin Ming Biotechnology Co., Ltd.	58
RD International Technology Co., Limited	58

Phosphoric acid, mono[1-[(hexadecyloxy)methyl]-2-(2,2,2-trifluoroethoxy)ethyl] mono(hydroxymethyl) ester MJ33-OH 199106-13-3 C22H43F3O6PLi C22H44F3O7P