POLY-L-HISTIDINE HYDROCHLORIDE MW
- CAS No.
- 26062-48-6
- Chemical Name:
- POLY-L-HISTIDINE HYDROCHLORIDE MW
- Synonyms
- polyhistidine;poly-L-histidine chloride;poly-L-HistidineMW5000-15000;POLY-L-HISTIDINE MOL WT 5000-15000;POLY-L-HISTIDINE HYDROCHLORIDE MW;Poly-L-histidine mol wt 5,000-25,000;POLY-L-HISTIDINE, HYDROCHLORIDE*MW 15,00 0-50,000
- CBNumber:
- CB4504157
- Molecular Formula:
- C6H9N3O2
- Molecular Weight:
- 155.16
- MDL Number:
- MFCD00166382
- MOL File:
- 26062-48-6.mol
POLY-L-HISTIDINE HYDROCHLORIDE MW price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | P9386 | Poly-L-histidine mol wt 5,000-25,000 | 26062-48-6 | 10mg | $157 | 2024-03-01 | Buy |
Sigma-Aldrich | P9386 | Poly-L-histidine mol wt 5,000-25,000 | 26062-48-6 | 50mg | $437 | 2024-03-01 | Buy |
Sigma-Aldrich | P9386 | Poly-L-histidine mol wt 5,000-25,000 | 26062-48-6 | 100mg | $805 | 2024-03-01 | Buy |
POLY-L-HISTIDINE HYDROCHLORIDE MW Chemical Properties,Uses,Production
Uses
Poly-L-histidine has been used:
- as a polycation for the dispersion of multi-wall carbon nanotubes (MWCNTs)
- as a polyionic compound to investigate its ability to rupture extracellular enveloped virus membrane
- in screening its anti-prion activity in cell based and in vivo anti-prion assay
Definition
ChEBI: Histidine is an alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3. It has a role as a metabolite. It is an alpha-amino acid, a member of imidazoles, an aromatic amino acid and a polar amino acid. It contains a 1H-imidazol-4-ylmethyl group. It is a conjugate base of a histidinium(1+). It is a conjugate acid of a histidinate(1-).
General Description
Poly-L-histidine is an amphoteric compound. The imidazole ring in its structure enables protonation?deprotonation.
Biochem/physiol Actions
Poly-L-histidine (Phis) copolymers are biocompatible, pH responsive and are less toxic. It exhibits endolysosomal escape funcationality. The copolymer of Phis with poly(ethylene glycol)?poly(d,l-lactide) (PEG-PLA) is effective in delivering doxorubicin. pH sensitive poly(l-histidine) copolymer micelles have application in delivering anticancer drugs in acidic microenvironment.
POLY-L-HISTIDINE HYDROCHLORIDE MW Preparation Products And Raw materials
Raw materials
Preparation Products
POLY-L-HISTIDINE HYDROCHLORIDE MW Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Beijing OKA biological technology co., LTD | 010-010-010-62971590 18548936886 | jack@oka-vip.com | China | 6897 | 58 |
Zhengzhou Convergence Chemical Co. LTD | 0371-53736046 13393710386 | 2853979814@qq.com | China | 10000 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
Hubei Guangao Biotechnology Co., Ltd | 027-027-59223056 18162699093 | 1208480011@qq.com | China | 9928 | 58 |
Hubei Wande Chemical Co., Ltd | 027-59210159 15377098680 | 1148280011@qq.com | China | 9974 | 58 |
Guangzhou Weihua Biotechnology Co., Ltd | 020-020-37239396 18922492046 | weihuasw@foxmail.com | China | 2198 | 58 |
Shanghai Maclean Biochemical Technology Co., LTD | 021-50706066 15221275939 | shenlinxing@macklin.cn | China | 29802 | 58 |