1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE
- CAS No.
- 75629-57-1
- Chemical Name:
- 1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE
- Synonyms
- CS-1229;Oncrasin 1;ZERO/008607;ZINC00439476;AKOS B014321;Oncrasin 1 >ASISCHEM N15726;ART-CHEM-BB B014321;CHEMBRDG-BB 5601604;1-(4-chlorobenzyl)indole-3-carbaldehyde
- CBNumber:
- CB4698434
- Molecular Formula:
- C16H12ClNO
- Molecular Weight:
- 269.73
- MDL Number:
- MFCD01051808
- MOL File:
- 75629-57-1.mol
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319 | |||||||||
Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
Hazard Codes | Xi | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 2933.99.9000 | |||||||||
HazardClass | IRRITANT | |||||||||
NFPA 704 |
|
1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE price More Price(28)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 496265 | Oncrasin-1 | 75629-57-1 | 25mg | $128 | 2023-06-20 | Buy |
Sigma-Aldrich | O0516 | Oncrasin-1 ≥98% (HPLC) | 75629-57-1 | 5mg | $109 | 2022-05-15 | Buy |
TCI Chemical | O0450 | Oncrasin 1 >95.0%(HPLC) | 75629-57-1 | 10mg | $112 | 2024-03-01 | Buy |
TCI Chemical | O0450 | Oncrasin 1 >95.0%(HPLC) | 75629-57-1 | 50mg | $390 | 2024-03-01 | Buy |
Alfa Aesar | J64018 | Oncrasin 1 | 75629-57-1 | 10mg | $128 | 2021-12-16 | Buy |
1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Chemical Properties,Uses,Production
Uses
Oncrasin 1 is a proapoptotic compound.
Definition
ChEBI: Oncrasin-1 is a member of the class of indoles that is 1H-indole substituted by 4-chlorobenzyl and formyl groups at positions 1 and 3, respectively. It is an anti-cancer agent that is active against lung cancer cells with K-Ras mutations. It has a role as an apoptosis inducer and an antineoplastic agent. It is a member of indoles, a member of monochlorobenzenes and an arenecarbaldehyde.
Biological Activity
Proapoptotic agent that induces abnormal nuclear aggregation of PKC ι and suppresses RNA transcription. Exhibits antiproliferative effects against various human tumor cell lines with K-Ras mutations (IC 50 ≤ 3 μ M) with minimal effects on normal epithelial cells and inhibits human xenograft growth by 75% in vivo .
storage
+4°C
1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
1-(4-CHLORO-BENZYL)-1 H-INDOLE-3-CARBALDEHYDE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10828 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
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