ChemicalBook >> CAS DataBase List >>1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE

1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE

CAS No.
688348-25-6
Chemical Name:
1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE
Synonyms
PDM 2;PDM-2;PDM2;PDM 2;688348-25-6;(E)-1,3-Dichloro-5-(4-chlorostyryl)benzene;1,3-dichloro-5-[(E)-2-(4-chlorophenyl)ethenyl]benzene;1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE;Benzene, 1,3-dichloro-5-[(1E)-2-(4-chlorophenyl)ethenyl]-;inhibit,Aryl Hydrocarbon Receptor,PDM2,PDM-2,PDM 2,Inhibitor,AhR
CBNumber:
CB4739467
Molecular Formula:
C14H9Cl3
Molecular Weight:
283.58
MDL Number:
MFCD08062175
MOL File:
688348-25-6.mol
Last updated:2023-05-21 10:59:17

1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE Properties

Boiling point 394.2±42.0 °C(Predicted)
Density 1.360±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 2 mg/ml
form A crystalline solid

1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10006342 PDM 2 ≥98% 688348-25-6 10mg $47 2024-03-01 Buy
Cayman Chemical 10006342 PDM 2 ≥98% 688348-25-6 50mg $206 2024-03-01 Buy
Cayman Chemical 10006342 PDM 2 ≥98% 688348-25-6 100mg $360 2024-03-01 Buy
ApexBio Technology C5219 PDM2 688348-25-6 100mg $389 2021-12-16 Buy
AK Scientific 1121AH 1,3-Dichloro-5-[(1E)-2-(4-chlorophenyl)ethenyl]-benzene 688348-25-6 100mg $499 2021-12-16 Buy
Product number Packaging Price Buy
10006342 10mg $47 Buy
10006342 50mg $206 Buy
10006342 100mg $360 Buy
C5219 100mg $389 Buy
1121AH 100mg $499 Buy

1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE Chemical Properties,Uses,Production

Description

The aryl hydrocarbon receptor (AhR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics, including dioxin, benzo[a]pyrene, and numerous polyaromatics from soot and coal tar. PDM 2 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor (AhR) antagonist, with a Ki of 1.2 nM. PDM 2 is inactive as a ligand for the estrogen receptor even at 100 μM. As AhR knockout mice are insensitive to the carcinogenic effects of classical AhR ligands, PDM 2 is a potential therapeutic for the treatment for dioxin and other aryl hydrocarbon poisonings.

1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE PDM 2 1,3-dichloro-5-[(E)-2-(4-chlorophenyl)ethenyl]benzene PDM-2;PDM2;PDM 2;688348-25-6 Benzene, 1,3-dichloro-5-[(1E)-2-(4-chlorophenyl)ethenyl]- inhibit,Aryl Hydrocarbon Receptor,PDM2,PDM-2,PDM 2,Inhibitor,AhR (E)-1,3-Dichloro-5-(4-chlorostyryl)benzene 688348-25-6