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PROTAC Linker 27

CAS No.
1246286-33-8
Chemical Name:
PROTAC Linker 27
Synonyms
Tos-PEG2-NH2;PROTAC Linker 27;2-(2-aminoethoxy)ethyl 4-methylbenzenesulfonate;Ethanol, 2-(2-aminoethoxy)-, 1-(4-methylbenzenesulfonate)
CBNumber:
CB48054814
Molecular Formula:
C11H17NO4S
Molecular Weight:
259.32
MDL Number:
MFCD32263212
MOL File:
1246286-33-8.mol
Last updated:2023-02-23 14:24:11

PROTAC Linker 27 Properties

Boiling point 414.5±30.0 °C(Predicted)
Density 1?+-.0.06 g/cm3(Predicted)
pka 8?+-.0.10(Predicted)

PROTAC Linker 27 Chemical Properties,Uses,Production

Biological Activity

Tos-PEG2-NH2 (PROTAC Linker 27) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

PROTAC Linker 27 Preparation Products And Raw materials

Raw materials

Preparation Products

PROTAC Linker 27 Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223 psaitong@jm-bio.com China 29834 58
Xi'an Qiyue Biotechnology Co., Ltd. 400-400-6966-012-012 17778955912 2957605606@qq.com China 2535 58
Shanghai Lamanda Pharmaceutical Technology Co., LTD 021-15601862 15601862873 15601862873@163.com China 129 58
Aobolihui 0917-18691729 18691729963 2553382659@qq.com China 4758 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 malulu@leyan.com China 40041 58
PROTAC Linker 27 Tos-PEG2-NH2 2-(2-aminoethoxy)ethyl 4-methylbenzenesulfonate Ethanol, 2-(2-aminoethoxy)-, 1-(4-methylbenzenesulfonate) 1246286-33-8 peg