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Bizelesin
- CAS No.
- 129655-21-6
- Chemical Name:
- Bizelesin
- Synonyms
- U-77779;Bizelesin;NSC-615291;(8S,8'S)-6,6'-[Carbonylbis(iMino-1H- indole-5,2-diylcarbonyl)]bis[8-(chloroMethyl)-3,6,7,8-tetrahydro-1-Methylbe;1,3-bis[2-[(8S)-8-(chloromethyl)-4-hydroxy-1-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-6-carbonyl]-1H-indol-5-yl]urea;N,N'-Bis[2-[[(1S)-1-(chloroMethyl)-1,6-dihydro-5-hydroxy-8-Methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]urea;Urea, N,N'-bis[2-[[(1S)-1-(chloromethyl)-1,6-dihydro-5-hydroxy-8-methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]-;1,3-Bis[2-[[[(8S)-8β-chloromethyl-3,6,7,8-tetrahydro-4-hydroxy-1-methylbenzo[1,2-b:4,3-b']dipyrrol]-6-yl]carbonyl]-1H-indol-5-yl]urea
- CBNumber:
- CB51016702
- Molecular Formula:
- C43H36Cl2N8O5
- Molecular Weight:
- 815.7
- MDL Number:
- MOL File:
- 129655-21-6.mol
Last updated:2022-12-21 16:56:50
| Density | 1.604±0.06 g/cm3(Predicted) |
|---|---|
| pka | 10.06±0.40(Predicted) |
| NCI Dictionary of Cancer Terms | bizelesin |
| FDA UNII | L0O9OBI87E |
| NCI Drug Dictionary | bizelesin |
Bizelesin price More Price(1)
Bizelesin Chemical Properties,Uses,Production
Uses
As members of the cyclopropylpyrroloindole family, Adozelesin and Bizelesin cause genomic DNA lesions by alkylating DNA. Adozelesin induces single-strand DNA lesions, whereas Bizelesin induces both si ngle-strand lesions and double-strand DNA cross-links. liferation by different pathways (i.e., Adozelesin induced apoptosis, and Bizelesin induced senescence).
Bizelesin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 20)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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129655-21-6(Bizelesin)Related Search:
1,3-Bis[2-[[[(8S)-8β-chloromethyl-3,6,7,8-tetrahydro-4-hydroxy-1-methylbenzo[1,2-b:4,3-b']dipyrrol]-6-yl]carbonyl]-1H-indol-5-yl]urea
NSC-615291
U-77779
(8S,8'S)-6,6'-[Carbonylbis(iMino-1H-
indole-5,2-diylcarbonyl)]bis[8-(chloroMethyl)-3,6,7,8-tetrahydro-1-Methylbe
N,N'-Bis[2-[[(1S)-1-(chloroMethyl)-1,6-dihydro-5-hydroxy-8-Methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]urea
Bizelesin
1,3-bis[2-[(8S)-8-(chloromethyl)-4-hydroxy-1-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-6-carbonyl]-1H-indol-5-yl]urea
Urea, N,N'-bis[2-[[(1S)-1-(chloromethyl)-1,6-dihydro-5-hydroxy-8-methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]-
129655-21-6
C43H36Cl2N8O5
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Indole Derivatives
Intermediates & Fine Chemicals
Pharmaceuticals