ChemicalBook >> CAS DataBase List >>Dehydroevodiamine
Dehydroevodiamine
- CAS No.
- 67909-49-3
- Chemical Name:
- Dehydroevodiamine
- Synonyms
- dehydrovodiamine;Dehydroevodiamine;14-Methyl-5(7H)-oxo-8,13-dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazoline-14-ium;8,13-Dihydro-14-methyl-5-oxoindolo[2',3':3,4]pyrido[2,1-b]quinazolinium inner salt;5,7,8,13-Tetrahydro-14-methyl-5-oxoindolo[2',3':3,4]pyrido[2,1-b]quinazolin-14-ium;Indolo[2',3':3,4]pyrido[2,1-b]quinazolinium,8,13-dihydro-14-methyl-5-oxo-, inner salt;14-Methyl-5-oxo-7,8-dihydro-5H-indolo[2',3':3,4]-pyrido[2,1-b]quinazolin-14-ium-13-ide
- CBNumber:
- CB51180199
- Molecular Formula:
- C19H15N3O
- Molecular Weight:
- 301.35
- MDL Number:
- MFCD11656140
- MOL File:
- 67909-49-3.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:09
Dehydroevodiamine price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 361774 | Dehydroevodiamine | 67909-49-3 | 20mg | $263 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD74260 | Dehydroevodiamine | 67909-49-3 | 100mg | $231 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb593872 | Dehydroevodiamine | 67909-49-3 | 100mg | $306 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0002661 | 14-METHYL-5-OXO-7,8-DIHYDRO-5H-INDOLO-[2',3',3,4]-PYRIDO[2,1-B]QUINAZOLIN-14-IUM-13-IDE 95.00% | 67909-49-3 | 5MG | $403.06 | 2021-12-16 | Buy |
| ChemScene | CS-0018627 | Dehydroevodiamine | 67909-49-3 | 5mg | $50 | 2021-12-16 | Buy |
Dehydroevodiamine Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from dried near-ripe fruit of Evodia sclerosus.
Uses
Dehydroevodiamine is a novel alkaloid which displays butyrylcholinesterase inhibitory activity in vivo.
Biological Activity
Dehydroevodiamine, a quinazoline alkaloid isolated from Evodiae Fructus, has antiarrhythmic effects on guinea pig ventricular myocytes. It inhibits LPS-induced expression of iNOS, COX-2, PGE2 and NF-κB in mouse macrophages.
Physiological effects
Dehydroevodiamine has an antihypertensive and antitumor effects.
in vitro
Dehydroevodiamine (0-50 μM; 2 hours) inhibits iNOS and COX-2 expression and prevents degradation of IκB-α in LPS induced RAW 264.7 macrophages. Dehydroevodiamine (0-50 μM; 2 hours) inhibits a LPS -induced increase in the iNOS and COX-2 mRNA expression.
Western Blot Analysis
| Cell Line: td> | RAW 264.7 macrophage cells |
| Concentration: | 10 μM, 30 μM, 50 μM |
| Incubation Time: | pretreated 2 hours |
| Result: | Reduced iNOS and COX-2 expression and increased IκB-α expression. |
RT-PCR
| RAW 264.7 macrophage cells | |
| Concentration: | 10 μM, 30 μM, 50 μM | td>
| Incubation Time: | pretreated 2 hours |
| Result: | Reduced iNOS and COX-2 mRNA expression. |
target
| Target | Value |
| NF-κB () | |
| COX-2 () | |
| iNOS () | |
| PGE2 () |
Dehydroevodiamine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 127)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8348 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
| Apeloa Pharmaceutical Co., Ltd. | +86-0571-87635730 +8615858229168 | chem1022@hengdian-group.com | China | 1469 | 58 |
View Lastest Price from Dehydroevodiamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Dehydroevodiamine
67909-49-3
|
US $0.00 / mg | 20mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2020-01-05 | Dehydroevodiamine
67909-49-3
|
US $1.00 / KG | 1KG | 95-99% | 1ton | Career Henan Chemical Co |
-
- Dehydroevodiamine
67909-49-3
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- Dehydroevodiamine
67909-49-3
- US $1.00 / KG
- 95-99%
- Career Henan Chemical Co
67909-49-3(Dehydroevodiamine)Related Search:
Dehydroevodiamine
14-Methyl-5(7H)-oxo-8,13-dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazoline-14-ium
5,7,8,13-Tetrahydro-14-methyl-5-oxoindolo[2',3':3,4]pyrido[2,1-b]quinazolin-14-ium
8,13-Dihydro-14-methyl-5-oxoindolo[2',3':3,4]pyrido[2,1-b]quinazolinium inner salt
14-Methyl-5-oxo-7,8-dihydro-5H-indolo[2',3':3,4]-pyrido[2,1-b]quinazolin-14-ium-13-ide
Indolo[2',3':3,4]pyrido[2,1-b]quinazolinium,8,13-dihydro-14-methyl-5-oxo-, inner salt
dehydrovodiamine
67909-49-3
reagent
standard substance