ISIS9271)
- CAS No.
- 177075-18-2
- Chemical Name:
- ISIS9271)
- Synonyms
- ISIS9271);ISIS5132(Synonyms:CGP69846A
- CBNumber:
- CB513378757
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| FDA UNII | 48IAF3FDP3 |
|---|
ISIS9271) Chemical Properties,Uses,Production
Uses
ISIS 5132 is a 20-base phosphorothioate oligonucleotide that specifically down-regulates c-raf expression.
References
[1] Rudin CM, Holmlund J, Fleming GF, et al. Phase I Trial of ISIS 5132, an antisense oligonucleotide inhibitor of c-raf-1, administered by 24-hour weekly infusion to patients with advanced cancer.?Clin Cancer Res. 2001;7(5):1214-1220. PMID:11350886
[2] Tolcher AW, Reyno L, Venner PM, et al. A randomized phase II and pharmacokinetic study of the antisense oligonucleotides ISIS 3521 and ISIS 5132 in patients with hormone-refractory prostate cancer.?Clin Cancer Res. 2002;8(8):2530-2535. PMID:12171880
ISIS9271) Preparation Products And Raw materials
Raw materials
Preparation Products
ISIS9271) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai meikai technology co., ltd | 021-68689288 15300790979 | info@mkbio.com.cn | China | 5000 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai meikai technology co., ltd | 58 |
