ChemicalBook >> CAS DataBase List >>7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) structure

CAS No.: 230615-70-0

Chemical Name:: 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)

Synonyms: C1sH2F3N3O;Vernicline API TFA;Varenicline Impurity 16;Varenicline Impurity 19;-2,2,2-trifluoroethanone;Varenicline N-Trifluoroacetyl;Varenicline N-Trifluoroacetyl Impurity;1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H);2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-6,10-methano-8H-pyraz...;8-(Trifluoroacetyl)-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline

CBNumber:: CB51512572

Molecular Formula:: C15H12F3N3O

Molecular Weight:: 307.27

MDL Number:: MFCD23701601

MOL File:: 230615-70-0.mol

MSDS File:: SDS

Last updated:2024-01-10 11:57:46

Request For Quotation

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) Properties

Melting point	164-166 ºC
Boiling point	491.9±45.0 °C(Predicted)
Density	1.449
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	1.50±0.20(Predicted)
form	Solid
color	White to Off-White
FDA UNII	22E2HV68CM

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) price More Price(10)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	T889503	7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine	230615-70-0	50mg	$425	2021-12-16	Buy
ChemScene	CS-B0007	1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H)-yl)-2,2,2-trifluoroethanone 98.95%	230615-70-0	100mg	$458	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0029454	7,8,9,10-TETRAHYDRO-8-(TRIFLUOROACETYL)-6,10-METHANO-6H-PYRAZINO[2,3-H][3]BENZAZEPINE 95.00%	230615-70-0	5MG	$504.45	2021-12-16	Buy
Matrix Scientific	098972	1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]-quinoxalin-8(7H)-yl)-2,2,2-trifluoroethanone 95+%	230615-70-0	250mg	$567	2021-12-16	Buy
AK Scientific	1495AB	1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H)-yl)-2,2,2-trifluoroethanone	230615-70-0	250mg	$815	2021-12-16	Buy

Product number	Packaging	Price	Buy
T889503	50mg	$425	Buy
CS-B0007	100mg	$458	Buy
HCH0029454	5MG	$504.45	Buy
098972	250mg	$567	Buy
1495AB	250mg	$815	Buy

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) Chemical Properties,Uses,Production

Description

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(trifluoroacetyl)varenicline) is an important pharmaceutical intermediate compound which is used in the preparation of varenicline. Varenicline is an oral smoking cessation aid drug. It works by blocking the pleasant effects of nicotine (from smoking) on the brain.

Uses

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine is used to prepare varenicline, which is a smoking cessation. It is a Varenicline protected impurity.

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) Preparation Products And Raw materials

Raw materials

Preparation Products

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) Suppliers

Global( 102)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8348	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
WinWin Chemical CO., Limited	+86-0577-64498589 +8615325081899	sales@win-winchemical.com	China	14157	58
Xi'an MC Biotech, Co., Ltd.	029-89275612 +8618991951683	mcbio_sales@163.com	China	2255	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
SIMAGCHEM CORP	58
WinWin Chemical CO., Limited	58
Xi'an MC Biotech, Co., Ltd.	58

View Lastest Price from 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacety 230615-70-0	US $7.00 / kg	1kg	99%	100kg	Career Henan Chemical Co

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacety
230615-70-0
US $7.00 / kg
99%
Career Henan Chemical Co

230615-70-0(7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline))Related Search:

Varenicline Impurity 5 (+/-)-2,2,2-trifluoro-1-(4-nitro-10-aza-tricyclo[6.3.1.02,7]dodeca-2(7),3,5-trien-10-yl)-ethanone Varenicline Impurity 17 N-Methyl Varenicline 5,9-Methanoimidazo[4,5-h][3]benzazepine,1,5,6,7,8,9-hexahydro-(9CI)

Varenicline-13C2,15N2 Varenicline Impurity 13 HCl N-Acetyl Varenicline N-Formyl Varenicline Varenicline-d4

2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine 2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine 7,8,9,10-Tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine 1,4-Dioxide 10-AZA-TRICYCLO[6.3.1.0]DODECA-2,4,6-TRIENE TOSYLATE 2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine

7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) Varenicline 6,7-DIMETHYLQUINOXALINE

1of4

6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)- (9CI) 2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-yl)ethanone 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)- 10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacetyl)- 1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]-quinoxalin-8(7H)-yl)-2,2,2-trifluoroethanone 1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H) -2,2,2-trifluoroethanone 2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxalin-8-yl)ethan-1-one 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-8-(trifluoroacety 2,2,2 - trifluoro - 1 - (6,7,9,10-tetrahydro- 8H - 6,10 -methanoazepino [4,5-g]quinoxaline- 8 - yl) ethan - 1 - one Varenicline Impurity 16 Ethanone, 2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-yl)- Varenicline N-Trifluoroacetyl Impurity Varenicline Impurity 19 2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-6,10-methano-8H-pyraz... Vernicline API TFA 8-(Trifluoroacetyl)-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline Varenicline N-Trifluoroacetyl C1sH2F3N3O 230615-70-0 API intermediates