ChemicalBook >> CAS DataBase List >>3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
- CAS No.
- 35286-58-9
- Chemical Name:
- 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
- Synonyms
- Gouguside 7;Kudinoside H;Zigu-glucoside I;Ziyu-glycoside Ⅰ;Ulmus pumila saponin I;3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester;Urs-12-en-28-oic acid, 3-(α-L-arabinopyranosyloxy)-19-hydroxy-, β-D-glucopyranosyl ester, (3β)-;3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester(Kudinoside H:Ziyuglycoside I);[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-1-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
- CBNumber:
- CB52462159
- Molecular Formula:
- C41H66O13
- Molecular Weight:
- 766.95
- MDL Number:
- MFCD13195536
- MOL File:
- 35286-58-9.mol
- MSDS File:
- SDS
Last updated:2023-05-21 10:59:17
| Melting point | 198-202 ºC |
|---|---|
| Boiling point | 841.9±65.0 °C(Predicted) |
| Density | 1.35 |
| storage temp. | -20°C, protect from light |
| solubility | Soluble in acetonitrile and methanol; |
| form | powder |
| pka | 12.52±0.70(Predicted) |
| color | White |
| Water Solubility | insoluble in water |
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL84269 | Ziyuglycoside I phyproof? Reference Substance | 35286-58-9 | 10MG | $435 | 2023-06-20 | Buy |
| Biosynth Carbosynth | MZ44395 | Ziyuglycoside I | 35286-58-9 | 50mg | $470 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573030 | 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester >98%,Standard References Grade | 35286-58-9 | 1g | $3432.3 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 107509 | ZiyuglycosideI | 35286-58-9 | 10mg | $556 | 2021-12-16 | Buy |
| ChemScene | CS-0008893 | ZiyuglycosideI 98.51% | 35286-58-9 | 5mg | $50 | 2021-12-16 | Buy |
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester Chemical Properties,Uses,Production
Chemical Properties
White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Burnet.
Uses
Used for content determination/identification/pharmacological experiments, etc.
Biological Activity
Ziyuglycoside I, isolated from the roots of S. officinalis, has anti-wrinkle activity and increases collagen type I expression. It can be used as an active ingredient in cosmetics and induces p53-mediated cell cycle arrest and apoptosis (apoptosis), which can be used in the study of triple-negative breast cancer.
Physiological effects
Ziyuglycoside I has the functions of vasoconstriction, hemostasis and antifungal.
in vitro
Ziyuglycoside I (5-160 μM; 24 hours) reveals a marked anti-proliferation activity with an IC 50 value of 13.96 μM in MDA-MB-231 cells. Ziyuglycoside I ( 5-20 μM; 24 hours) induces MDA-MB-231 cell apoptosis by increasing the percentage of apoptotic cells from 2.43% to 44.76% at 20 μM. Ziyuglycoside I (5-20 μM; 24 hours) induces the cleavage of caspas- 8, caspase-9, and caspase-3, up-regulates the pro-apoptotic protein Bax, and down-regulates anti-apoptotic protein Bal-2, dose-dependently reduces the level of mito-cyto c expression.
Cell Viability Assay
| Cell Line: | MDA-MB-231 cells < /td> |
| Concentration: | 5 μM, 10 μM, 20 μM, 40 μM, 80 μM, and 160 μM |
| Incubation Time: | 24 hours |
| Result: | Showed cytotoxicity on MDA-MB-231 cells. |
Cell Cycle Analysis
| Cell Line: | MDA-MB-231 cells |
| Concentration: | 5 μM, 10 μM, and 20 μM |
| Incubation Time: | 24 hours |
| Result: | Induced G2/M phase arrest and apoptosis on MDA-MB-231 Cells |
Western Blot Analysis
| Cell Line: | MDA-MB-231 cells |
| Concentration: | 5 μM, 10 μM, and 20 μM |
| Incubation Time: | 24 hours |
| Result: | Induced apoptosis in MDA-MB-231 Cells through Intrinsic and Extrinsic Pathways. |
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 137)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8349 | 58 |
View Lastest Price from 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-23 | ziyu-glycoside I; 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
35286-58-9
|
US $0.00 / KG | 1KG | 60%-98% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2023-02-24 | Ziyuglycoside I
35286-58-9
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- ziyu-glycoside I; 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
35286-58-9
- US $0.00 / KG
- 60%-98% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Ziyuglycoside I
35286-58-9
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
35286-58-9(3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester)Related Search:
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
Kudinoside H
Zigu-glucoside I
Gouguside 7
Ulmus pumila saponin I
Ziyu-glycoside Ⅰ
Urs-12-en-28-oic acid, 3-(α-L-arabinopyranosyloxy)-19-hydroxy-, β-D-glucopyranosyl ester, (3β)-
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-1-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester(Kudinoside H:Ziyuglycoside I)
35286-58-9
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract