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Chonglou Saponin VII

Chonglou Saponin VII structure

CAS No.: 68124-04-9

Chemical Name:: Chonglou Saponin VII

Synonyms: Dioscinin;Paris VII;Polyphyllin VIT;Chonglouoside Ⅶ;Chonglouoside Ⅶ;Chonglou SaponinG;Paris saponin VII;Chonglou saponin Ⅶ;Chonglou Saponin VII;β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-6-deoxy-α-L-mannopyranosyl-(1→4)-6-deoxy-α-L-mannopyranosyl-(1→4)]-

CBNumber:: CB52519622

Molecular Formula:: C51H82O21

Molecular Weight:: 1031.2

MDL Number:: MFCD20260362

MOL File:: 68124-04-9.mol

MSDS File:: SDS

Last updated:2023-09-20 16:43:00

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Chonglou Saponin VII Properties

Melting point	243-245 °C (decomp)
Density	1.45±0.1 g/cm3(Predicted)
storage temp.	-20°C, protect from light
solubility	Soluble in methanol;
pka	12?+-.0.70(Predicted)
form	powder
color	White
Water Solubility	sparingly soluble in water

SAFETY

Risk and Safety Statements

HS Code	29329990

Chonglou Saponin VII price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0023885	ParissaponinVII 99.13%	68124-04-9	5mg	$135	2021-12-16	Buy
ChemScene	CS-0023885	ParissaponinVII 99.13%	68124-04-9	10mg	$230	2021-12-16	Buy
American Custom Chemicals Corporation	PXT0005387	CHONGLOU SAPONIN VII 95.00%	68124-04-9	5MG	$459.96	2021-12-16	Buy
Biosynth Carbosynth	OC42613	Chonglou Saponin VII	68124-04-9	10mg	$800	2021-12-16	Buy
AK Scientific	W2311	ChonglouSaponinVII	68124-04-9	10mg	$1130	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0023885	5mg	$135	Buy
CS-0023885	10mg	$230	Buy
PXT0005387	5MG	$459.96	Buy
OC42613	10mg	$800	Buy
W2311	10mg	$1130	Buy

Chonglou Saponin VII Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents.

Uses

Used for content determination/identification/pharmacological experiments, etc.

Biological Activity

Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii Maxim. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with inhibition of Akt/p38 MAPK and P-gp. It attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins (Bax and cytochrome c), and reduces the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1 and p-Akt. Paris saponin VII induces strong autophagy in K562/ADR cells, which can be used for leukemia research.

Pharmacology

Chonglou saponin VII has the functions of anti-inflammatory, anti-tumor, anti-viral, lowering cholesterol, lowering blood pressure and so on.

in vitro

Paris saponin VII (Chonglou Saponin VII) inhibits the growth of adriamycin-resistant human leukemia cells (K562/ADR) in a dose-dependent manner. It significantly suppresses cell proliferation by cell cycle arrest in the G0 /G1 phase.

in vivo

Paris saponin VII (Chonglou Saponin VII) (intravenous administration) significantly enhances anticancer efficacy of adriamycin to MCF-7/ADR xenograft model in nude mice.

target

Akt

p38

Bcl-2

Caspase-9

Caspase-3

PARP-1

Chonglou Saponin VII Preparation Products And Raw materials

Raw materials

Preparation Products

Chonglou Saponin VII Suppliers

Global( 95)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8349	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10326	58
Apeloa Pharmaceutical Co., Ltd.	+86-0571-87635730 +8615858229168	chem1022@hengdian-group.com	China	1469	58

Supplier	Advantage
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Shanghai Standard Technology Co., Ltd.	58
career henan chemical co	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
Wuhan ChemNorm Biotech Co.,Ltd.	58
Hubei Ipure Biology Co., Ltd	58
Apeloa Pharmaceutical Co., Ltd.	58

View Lastest Price from Chonglou Saponin VII manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2023-02-24	Chonglou Saponin VII 68124-04-9	US $0.00 / mg	5mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.
	2020-01-10	Chonglou Saponin VII 68124-04-9	US $9.80 / KG	1KG	≥98%	20 tons	Career Henan Chemical Co

Chonglou Saponin VII
68124-04-9
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

Chonglou Saponin VII
68124-04-9
US $9.80 / KG
≥98%
Career Henan Chemical Co

Chonglou Saponin VII Spectrum

Chonglou Saponin VII(68124-04-9)¹HNMR

68124-04-9(Chonglou Saponin VII)Related Search:

Chonglou Saponin II PolyphyllinH (25R)-3β-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene ANTI-GALECTIN-7 Dioscin

POLYPHYLLIN B (RG) Pennogenin3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside ALLEOSIDE A (3beta,25R)-14-Hydroxyspirost-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-[beta-D-xylopyranosyl-(1-4)]-beta-D-glucopyranoside POLYPHYLLIN D

22,25-Epoxy-2,3,14,20-tetrahydroxycholest-7-en-6-one Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv. Bufalin Bufotaline Polyphyllin VI

Resibufogenin Polyphyllin VII beta-Sitosterol

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Chonglou Saponin VII Paris VII Chonglouoside Ⅶ Polyphyllin VIT β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-6-deoxy-α-L-mannopyranosyl-(1→4)-6-deoxy-α-L-mannopyranosyl-(1→4)]- Chonglou saponin Ⅶ Dioscinin Paris saponin VII Chonglouoside Ⅶ Chonglou SaponinG 68124-04-9