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Homoarginine

Homoarginine structure

CAS No.: 156-86-5

Chemical Name:: Homoarginine

Synonyms: C01924;l-lysin;H-HAR-OH;H-HOARG-OH;HOMOARGININE;H-HOMOARG-OH;L-HomoArg-OH;L-HOMOARGININE;H-HOMOARGININE;Homo-L-arginine

CBNumber:: CB5298985

Molecular Formula:: C7H16N4O2

Molecular Weight:: 188.23

MDL Number:: MFCD00237108

MOL File:: 156-86-5.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

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Homoarginine Properties

Melting point	207-209 °C
Boiling point	376.3±52.0 °C(Predicted)
Density	1.39±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
pka	2.52±0.24(Predicted)
CAS DataBase Reference	156-86-5(CAS DataBase Reference)
FDA UNII	JF751CK38I

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H312-H332
Precautionary statements	P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501

Homoarginine price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	H585008	Homoarginine	156-86-5	10g	$220	2021-12-16	Buy
ChemScene	CS-W008385	H-HoArg-OH ≥98.0%	156-86-5	100g	$278	2021-12-16	Buy
Chem-Impex	03989	L-Homoarginine ≥ 99% (Assay)	156-86-5	5G	$30	2021-12-16	Buy
Activate Scientific	AS92343	L-Homoarginine 95% ee	156-86-5	5G	$99	2021-12-16	Buy
ChemPep	180132	H-HoArg-OH	156-86-5	5g	$142	2021-12-16	Buy

Product number	Packaging	Price	Buy
H585008	10g	$220	Buy
CS-W008385	100g	$278	Buy
03989	5G	$30	Buy
AS92343	5G	$99	Buy
180132	5g	$142	Buy

Homoarginine Chemical Properties,Uses,Production

Description

Homoarginine and 1-hydroxyhomoarginine were originally detected in significant concentration in the seeds of many Lathyrus species (Bell, 1962a,b; 1963). Homoarginine was isolated from the seeds of L. cicera (Bell, 1962b) and L. sativus (Rao et al., 1963). The hydroxy compound was obtained from the seeds of L. tingitanus (Bell, 1964). The comparative distribution of guanidino compounds in the seeds of two genus of the Papilionoideae, Lathyrus and Vicia, exhibits interesting features (Bell and Tirimanna, 1964). For example, the genus Lathyrus stores predominantly the C7 amino acids homoarginine, y-hydroxyhomoarginine and the related compound lathyrine, while the genus Vicia stores relatively high concentrations of canavanine and of the C6 amino acids arginine and y-hydroxyarginine. Apart from plants, homoarginine was found in small amounts in human body fluids ,. urine (Armstrong, 1967), serum (Matsumoto et al., 1976a) and cerebrospinal fluid (Mori et al., 1981b) and in mammalian brain (Mori et al., 1978, 1979 ). Increased urinary excretion was reported in hyperlysinemia (Armstrong and Robinow, 1967) and citrullinemia (Scott-Emuakpor et al., 19(2).
Homoarginine may be formed in mammals from lysine, by a homologous urea cycle in which arginine is replaced by lysine (Ryan and Wells, 1964; Scott-Emuakpor et al., 19(2). The excretion of homocitrulline and homoarginine in urine following administration of lysine to children supports this theory (Buergi et al., 1966). The biosynthesis of homoarginine has not been examined in plants, but y-hydroxyhomoarginine is synthesized from homoarginine in Lathyrus seeds (Bell, 1964). Subsequently both compounds have been identified as the precursors of the cyclic guanidino derivative, lathyrine, also present in Lathyrus seeds (Bell and Przybylska, 1965). Homoarginine and y-hydroxyhomoarginine probably serve as nitrogen reserves in Lathyrus seeds.
Inhibition of growth by homoarginine has been reported In various microorganisms (Walker, 1955; Rao et al., 1963).
gama-Hydroxyhomoarginine lactone isolated from the seeds of L. tingitanus (Bell, 1964) probably results from the cyclization of the open chain compound under acidic conditions.

Chemical Properties

White to off-white powder

Uses

Homoarginine is an inhibitor of human arginase activity.

Uses

Homoarginine as marker for exogenous protein
Absorption and secretion of free homoarginine in the intestine: when 9 mmol homoarginine were infused into the proximal part of the jejunum, there was a 99.9% disappearance of the free amino acid homoarginine up to the ileum. In addition, following the infusion of 9 mmol homoarginine into the vena jugularis less than 0.2% of the infused homoarginine appeared in the intestine.
We concluded from these data that with the homoarginine method endogenous protein in the chyme of the intestine can be distinguished from the food protein as homoarginine is not incorporated into endogenous secreta and free homo arginine is completely absorbed.

Definition

ChEBI: An L-lysine derivative that is the L-enantiomer of homoarginine.

Homoarginine Preparation Products And Raw materials

Raw materials

Preparation Products

Homoarginine Suppliers

Global( 180)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2931	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12468	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Accela ChemBio Inc.	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
Zhengzhou Alfa Chemical Co.,Ltd	58

View Lastest Price from Homoarginine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-09-29	Homoarginine 156-86-5	US $0.00 / Kg/Drum	1KG	98%min	500kgs	WUHAN FORTUNA CHEMICAL CO., LTD
2021-07-02	L-homoarginine 156-86-5	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2019-07-06	Homoarginine 156-86-5	US $1.00 / KG	1KG	99%	20kg	Career Henan Chemical Co

Homoarginine
156-86-5
US $0.00 / Kg/Drum
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

L-homoarginine
156-86-5
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Homoarginine
156-86-5
US $1.00 / KG
99%
Career Henan Chemical Co

Homoarginine Spectrum

Homoarginine(156-86-5)MS

156-86-5(Homoarginine)Related Search:

ARGINASE L(+)-Arginine L-HOMOCITRULLINE (S)-4-ACETOXY-2-AMINO-BUTYRIC ACID H-HOMOPRO-OME HCL

H-HomoPhe-OtBu.HCl (αS)-α-AMino-benzenebutanoic Acid Methyl Ester Hydrochloride L-BETA-HOMOLEUCINE HYDROCHLORIDE H-HomoArg(Boc)2-OH arginine aspirin

L(+)-Homoarginine hydrochloride BOC-N-OMEGA-(NITRO)-L-HOMOARGININE,BOC-HOMOARGININE(NO2)-OH,Boc-N-Nitro-L-HomoArginine D-Homoarginine hydrochloride BOC-HOMOARGININE HCL,BOC-L-HOMOARGININE BOC-L-BETA-HOMOARGININE(TOS)

FMOC-HOMOARGININE(PMC)-OH,FMOC-N-OMEGA-(2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONYL)-L-HOMOARGININE 6-GUANIDINOHEXANOIC ACID FMOC-L-HOMOARGININE, HYDROCHLORIDE SALT

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l-lysin l-n(sup6)-amidinolysine n(sup6)-(aminoiminomethyl)-l-lysin L-HOMOARGININE L-ALPHA-AMINO-EPSILON-GUANIDINOHEXANOIC ACID H-HOMOARG-OH H-HOARG-OH H-HAR-OH HOMOARGININE (2S)-2-amino-6-(diaminomethylideneamino)hexanoic acid Homo-L-arginine H-HOMOARGININE L-LYSINE, N6-(AMINOIMINOMETHYL)- (S)-2-AMINO-6-GUANIDINOHEXANOIC ACID L-α-Amino-ε-guanidinohexanoic acid N6-Amidino-L-lysine C01924 H-HoMoarg-OH(H-HoMoarginine) L-a-AMino-e-guanidinohexanoic acid L-Homoarginine≥ 99% (Assay) L-HomoArg-OH 1-(1,1,2,2-tetrafluoroethoxy)-4-[2-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]propan-2-yl]benzene Homoarginine USP/EP/BP Valine Impurity 28 Homoarginine,97% L-Homo-Arginine-OH 156-86-5 Amino Acids Chiral Compound Unusual Amino Acids