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Nampt-IN-1

Nampt-IN-1 Structure
Nampt-IN-1 structure
CAS No.
1698878-14-6
Chemical Name:
Nampt-IN-1
Synonyms
LSN3154567;Nampt-IN-1;Nampt inhibitor 1;LSN3154567 (Nampt-IN-1);LSN 3154567;LSN-3154567;LSN3154567;2-hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-;2-Hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]-1-propanesulfonamide;2-hydroxy-2-methyl-N-(2-(2-(pyridin-3-yloxy)acetyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)propane-1-sulfonamide;1-Propanesulfonamide, 2-hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]-;LSN-3154567,NAMPT,PBEF,Nampt IN 1,Visfatin,inhibit,Pre-B cell colony enhancing factor,Nicotinamide phosphoribosyl transferase,Inhibitor,NamptIN1,LSN 3154567
CBNumber:
CB53048664
Molecular Formula:
C20H25N3O5S
Molecular Weight:
419.49
MDL Number:
MFCD28963946
MOL File:
1698878-14-6.mol
Last updated:2023-04-23 13:52:06
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Nampt-IN-1 Properties

Boiling point 659.9±65.0 °C(Predicted)
Density 1.363±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: Soluble
form powder
pka 8.67±0.20(Predicted)
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Nampt-IN-1 price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2249 LSN3154567 ≥98% (HPLC) 1698878-14-6 5mg $107 2024-03-01 Buy
Sigma-Aldrich SML2249 LSN3154567 ≥98% (HPLC) 1698878-14-6 25mg $430 2024-03-01 Buy
Cayman Chemical 26066 Nampt-IN-1 ≥98% 1698878-14-6 1mg $44 2024-03-01 Buy
Cayman Chemical 26066 Nampt-IN-1 ≥98% 1698878-14-6 5mg $172 2024-03-01 Buy
Cayman Chemical 26066 Nampt-IN-1 ≥98% 1698878-14-6 10mg $321 2024-03-01 Buy
Product number Packaging Price Buy
SML2249 5mg $107 Buy
SML2249 25mg $430 Buy
26066 1mg $44 Buy
26066 5mg $172 Buy
26066 10mg $321 Buy

Nampt-IN-1 Chemical Properties,Uses,Production

Description

Nampt-IN-1 is a potent inhibitor of nicotinamide phosphoribosyltransferase (Nampt; IC50 = 3.1 nM). It is selective for Nampt over a panel of greater than 100 human kinases at 1 μM. Nampt-IN-1 inhibits NAD+ formation in and proliferation of HCT116 cells (IC50s = 1.8 and 8.9 nM, respectively). It inhibits cell growth in a panel of cancer cell lines (IC50s = <0.2-2 μM). Nampt-IN-1 inhibits NAD+ formation in an A2780 ovarian carcinoma mouse xenograft model (ED50 = 2 mg/kg).

Uses

Nampt-IN-1 functions as a co-drug. Nampt-IN-1 is a potent and selective NAMPT inhibitor.

Biochem/physiol Actions

LSN3154567 might be useful in developing a novel cancer therapeutic.

Nampt-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

Nampt-IN-1 Suppliers

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32715 60
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Nanjing Doge Biomedical Technology Co., Ltd 		+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 4691 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4182 55
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Zhejiang J&C Biological Technology Co.,Limited 		58
Nanjing Doge Biomedical Technology Co., Ltd 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
Amadis Chemical Company Limited 		58
Shanghai Boyle Chemical Co., Ltd. 55
Haoyuan Chemexpress Co., Ltd. 61
Shanghai Lollane Biological Technology Co.,Ltd. 55

1698878-14-6(Nampt-IN-1)Related Search:

N-Methyldiethanolamine N-Methylbenzylamine 2-Methylaminoethanol N-Methylbenzamide 2,2-DIMETHYLTETRAHYDROFURAN
Nampt-IN-1 2-hydroxy-2-methyl-N-(2-(2-(pyridin-3-yloxy)acetyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)propane-1-sulfonamide 2-Hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]-1-propanesulfonamide LSN3154567 (Nampt-IN-1) LSN3154567 2-hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6- LSN 3154567;LSN-3154567;LSN3154567 Nampt inhibitor 1 1-Propanesulfonamide, 2-hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]- LSN-3154567,NAMPT,PBEF,Nampt IN 1,Visfatin,inhibit,Pre-B cell colony enhancing factor,Nicotinamide phosphoribosyl transferase,Inhibitor,NamptIN1,LSN 3154567 1698878-14-6