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4-bromo-N'-butylbenzohydrazide

4-bromo-N'-butylbenzohydrazide Structure
4-bromo-N'-butylbenzohydrazide structure
CAS No.
537672-41-6
Chemical Name:
4-bromo-N'-butylbenzohydrazide
Synonyms
UF 010;CS-2427;UF010, >98%;UF-010; UF 010;UF010 >=98% (HPLC);4-Bromo-N'-butylbenzohydrazide;4-bromo-N'-butylbenzohydrazide;4-Bromobenzoic acid 2-butylhydrazide;Benzoic acid, 4-bromo-, 2-butylhydrazide;UF010,HDAC,UF-010,UF 010,Histone deacetylases,Inhibitor,inhibit
CBNumber:
CB53049247
Molecular Formula:
C11H15BrN2O
Molecular Weight:
271.15
MDL Number:
MFCD03603083
MOL File:
537672-41-6.mol
Last updated:2024-07-02 08:55:11
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4-bromo-N'-butylbenzohydrazide Properties

storage temp. Sealed in dry,Store in freezer, under -20°C
solubility insoluble in H2O; ≥10.65 mg/mL in DMSO; ≥20.85 mg/mL in EtOH
form solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
NFPA 704
0
2 0

4-bromo-N'-butylbenzohydrazide price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 21273 UF010 ≥98% 537672-41-6 5mg $44 2024-03-01 Buy
Cayman Chemical 21273 UF010 ≥98% 537672-41-6 10mg $78 2024-03-01 Buy
Cayman Chemical 21273 UF010 ≥98% 537672-41-6 25mg $172 2024-03-01 Buy
Cayman Chemical 21273 UF010 ≥98% 537672-41-6 50mg $321 2024-03-01 Buy
TRC B680880 4-Bromo-2-butylhydrazideBenzoicAcid 537672-41-6 25mg $165 2021-12-16 Buy
Product number Packaging Price Buy
21273 5mg $44 Buy
21273 10mg $78 Buy
21273 25mg $172 Buy
21273 50mg $321 Buy
B680880 25mg $165 Buy

4-bromo-N'-butylbenzohydrazide Chemical Properties,Uses,Production

Description

UF010 is a class I HDAC inhibitor with IC50 values of 0.06, 0.1, 0.5, and 1.5 μM for HDAC3, 2, 1, and 8, respectively. It is more than 6-fold selective for these class I HDACs over any additional HDACs. UF010 is reported to inhibit cancer cell proliferation with a mean GI50 value of 2.94 μM when screened against the NCI-60 panel of cancer cell lines and functions by blocking the G1/S phase of the cell cycle.

Uses

4-Bromo-2-butylhydrazide Benzoic Acid inhibits histone deacetylases (HDAC) as potential clinical anticancer therapies.

References

[1]. wang y, stowe rl, pinello ce, et al. identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class i histone deacetylases. chem biol, 2015, 22(2): 273-284.

4-bromo-N'-butylbenzohydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

4-bromo-N'-butylbenzohydrazide Suppliers

Global( 77)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32836 60
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10522 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24738 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Zhejiang J&C Biological Technology Co.,Limited 		58
InvivoChem 		58
LEAP CHEM CO., LTD. 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58

4-bromo-N'-butylbenzohydrazide Spectrum

4-bromo-N'-butylbenzohydrazide(537672-41-6)1HNMR
4-bromo-N'-butylbenzohydrazide UF 010 4-Bromobenzoic acid 2-butylhydrazide CS-2427 UF-010; UF 010 UF010, >98% Benzoic acid, 4-bromo-, 2-butylhydrazide UF010 >=98% (HPLC) UF010,HDAC,UF-010,UF 010,Histone deacetylases,Inhibitor,inhibit 4-Bromo-N'-butylbenzohydrazide 537672-41-6